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Target-capture polymerase chain reaction measures hepatitis B load accurately

Published in Blood Weekly, February 3rd, 2005

Target-capture polymerase chain reaction measures hepatitis B load accurately.

"Recent clinical studies suggest that hepatitis B virus (HBV) load and genotype may be independent predictors of responses to antiviral therapies. However, it is difficult for clinicians to accurately determine viral loads in patient samples because results- both the values and the units of measure- can vary greatly among different tests. Accordingly, the World Health Organization (WHO) has produced the first international standard for HBV DNA for nucleic acid amplification technology (NAT) assays," investigators in the United States report.

"In the present study, we...

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