Embryonic Stem Cell Research
Functional neurons generated by directed differentiation from ESCs
Published in Blood Weekly, February 3rd, 2005
"Embryonic stem (ES) cells are pluripotent cells that are derived from the inner cell mass of blastocysts. We produced neuronal cells by directed differentiation of a newly established murine ES cell line in vitro (Royan B1).
"Immunohistochemistry, scanning electron microscopy, Campenot's assay and electrophysiology were used to evaluate the differentiated neurons," researchers in Iran report.
"Antibodies against microtubule-associated protein (MAP2), glutamic acid decarboxylase (GAD) and tyrosine hydroxylase (TH) antigens showed that the...
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Source: Blood Weekly (2005-02-03)
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