Published in Blood Weekly, February 10th, 2005
"A critical early event in the HIV type 1 (HIV-1) particle assembly pathway is the targeting of the Gag protein to the site of virus assembly. In many cell types, assembly takes place predominantly at the plasma membrane. Cellular factors that regulate Gag targeting remain undefined," scientists in the United States report.
"The phosphoinositide phosphaticlylinositol (4,5) bisphosphate [PI(4,5)P-2] controls the plasma membrane localization of a number of...
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