Blood Weekly

Biomedical Engineering - Sintered polymeric microsphere matrix used for tissue-engineered bone formation

Embryonic Stem Cell Research - Embryos derived from PSOS SCs exhibit enhanced preimplantation development

Embryonic Stem Cell Research - Endothelial cells within embryonic muscles are source of myogenic progenitors

Hematology - Heme-degrading capacity of RES does not surpass ability to eliminate bilirubin

Neurogenesis - CNS SCs differentiate into functional neuronal circuits in 3-D collagen gels

Acute Lymphoblastic Leukemia - Intensive chemotherapy and imatinib rapidly induces CR in BCR-ABL+ AML patients

Acute Myelogenous Leukemia 1 - Hematopoietic potential of AML1 closely related to its transcriptional activity

Acute Myeloid Leukemia - Myeloid cell surface marker identified that is associated with AML

Alloreactivity - CFC depletes alloreactive T cells/retains broad specificity for other stimuli

Angioplasty - Rapamycin foils restenosis by blocking leukocytes and precursor cells

Antibacterial Activity - Amphiphilic polynorbornene derivatives studied, role of hydrophobicity clarifed

Antimicrobial Resistance - Antimicrobial use in equine hospitals lead to multidrug-resistant Salmonella

Apoptosis - P-selectin glycoprotein ligand-1 cross-linking induces activated T cell death

Biomedical Engineering - Fetal cells in mother rats assist liver and kidney remodeling after injury

Bioterrorism - Bioterrorist attack easier to control at onset rather than waiting for spread

Bioterrorism - National preparedness for bioterrorist attack is still weak

Bone Marrow Transplantation - Early genoidentical BMT increases ALL survival over late high-dose therapy/BMT

Breast Cancer - BRCA2 rearrangements in male breast cancer families without BRCA1/2 mutations

Business Update - Company reports demand for its Dengue Fever Test Kit

Cardiology - Beneficial cardiac effects of arteriovenous fistula closure are blunted

Cardiomyocytes - Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter cell cycle

Cardiomyocytes - Nonhematopoietic MSC can mobilize/differentiate into cardiomyocytes after MI

Cardiovascular Disease - DiOHF is able to prevent vascular reperfusion injury

Cholesterol - Kir2.1 channels analyzed, cholesterol effect and lipid raft targeting revealed

Chronic Myeloid Leukemia - AHSCT outcome in atypical CML not worse than in patients with BCR-ABL+ CML

Cirrhosis - Proteinuria diminishes after hepatitis C-related liver transplantation

Clostridium Perfringens -  Clostridium perfringens can adapt to low temperatures

Collaborations - Companies extend agreement, market iron preparations in the U.S. and Canada

Dengue Virus - Sustained dengue outbreak due to repeated introductions of different strains

Diagnostics - Sensitivity/concordance validated lab testing Salmonella-spiked baby food

Disease Control - Mortality increase in Russia attributed to preventable noncommunicable diseases

Embryonic Stem Cell Research - Notch1 required for establishment of long-term/definitive HSCs

Enterovirus 71 - Short hairpin RNAs developed to selectively inhibit enterovirus 71 replication

Epidemiology - Branching model estimates spread of infectious diseases in varying environments

Ewing Family Tumors - Thirty-seven genes identified that are up-regulated in Ewing family tumors

Exercise - Hemoglobin mass increase at altitude smaller in women than in men

Exosomes - Exosomes internalized/processed by immature DCs for presentation to CD4+ cells

Finance - Blood substitute developer announces offering of common stock

Gastroenterology - Graft size is critical in living donor liver transplantations

Genomics & Genetics - p51/p63 essential for epidermal-mesenchymal interactions

Genotoxicity - Acrylamide may impair DNA repair

HIV/AIDS Drug Resistance - Higher viral load/lower age correlate to nelfinavir-related L90M mutation

HIV/AIDS Drug Resistance - K65R mutations correlate negatively with thymidine analogue mutations

HIV/AIDS Impact - Disproportionate HIV/AIDS impact on racial/ethnic minorities examined

HIV/AIDS Pathogenesis - CD8 cells in HIV infection display profound down-modulation of CD7 expression

HIV/AIDS Pathogenesis - Conserved residues in HIV-1 gp41 coiled-coil pocket essential for replication

HIV/AIDS Pathogenesis - Continuous activation of naive T cells in children may be factor in CD4 decrease

HIV/AIDS Pathogenesis - Env quasispecies evolve from host-selective pressure despite viral suppression

HIV/AIDS Pathogenesis - HIV antigen persistence may trigger expansion of CD4+CD25+ regulatory T cells

HIV/AIDS Pathogenesis - HIV genome degradation after minus-strand synthesis occurs via Rnase H cleavage

HIV/AIDS Pathogenesis - HIV-1 Nef mediates neural cell death via IP-10 cytotoxicity

HIV/AIDS Pathogenesis - HIV-1 Vif interacts with dimerization sites of viral protease

HIV/AIDS Pathogenesis - HIV-1 favors the persistence of infection by activating macrophages through TNF

HIV/AIDS Pathogenesis - New lymphocyte population is overexpressed in HIV-infection

HIV/AIDS Pathogenesis - No correlation between HIV fusion peptides and their membrane affinities

HIV/AIDS Pathogenesis - Plasmacytoid dendritic cells reservoirs for HIV dissemination

HIV/AIDS Pathogenesis - RON inhibits HIV-1 transcription in monocytes/macrophages

HIV/AIDS Pathogenesis - Vif is an auxiliary factor of HIV-1 RT and facilitates abasic site bypass

HIV/AIDS Pathogenesis - Viral challenge induces suppression of genes regulating innate immunity

HIV/AIDS Research - Antibodies against HIV-1 V3 loop partially inhibit dendritic cell-SIGN binding

HIV/AIDS Research - HIV-1 populations in blood and breast milk are similar

HIV/AIDS Research - siRNA targeted to the HIV-1 primer binding site can inhibit virus replication

HIV/AIDS Screening - EIA is acceptable for HIV surveillance in urine samples of high-risk populations

HIV/AIDS Therapy - CYP2C19 converts nelfinavir to a bioactive metabolite

HIV/AIDS Therapy - IL-7 and Flt-3L plasma levels increased during HAART-associated IL-2 therapy

HIV/AIDS Therapy - Poly(ethylene glycol)-based saquinavir prodrug conjugates synthesized

HIV/AIDS Therapy - Recent studies add new data to HIV/AIDS therapy research

HIV/AIDS-Related Apoptosis - Morphine aggravates the apoptosis of SIV-infected cells

HIV/AIDS-Related Dementia - Predictive model developed for AIDS dementia complex

HIV/AIDS-Related Immunology - IL-8 responsiveness defines subset of CD8 T cells poised to kill

HIV/AIDS-Related Infection - Lymphoid interstitial pneumonia resolved through antiretroviral therapy

HIV/AIDS-Related Neuropathy - Erythropoietin is neuroprotective in HIV sensory neuropathy models

HIV/Tuberculosis Coinfection - Survival time is decreased for HIV patients with drug-resistant tuberculosis

Hematology - Japan should implement new screening procedures for blood donations

Hematology - Novel COX-2 variant expressed by platelets in some patients after CABG

Hematology - Quality of life indices rise in chronic hepatitis C patients on epoetin alfa