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Microbial Resistance

Carbapenem & ciprofloxacin most effective antimicrobials for ESBL-EK bacteremia

Published in Blood Weekly, February 24th, 2005

Carbapenem & ciprofloxacin are the most effective antimicrobials for extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia.

According to a study from South Korea, "This study was conducted to evaluate risk factors for mortality and treatment outcome of bloodstream infections due to extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EK).

"ESBL production in stored K. pneumoniae and E. coli blood isolates from Jan 1998 to Dec 2002 was phenotypically determined according to NCCLS guidelines and/or the double-disk synergy...

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