Tissue Engineering
Collagen IX provides a mechanism for cell adhesion to cartilaginous matrix
Published in Blood Weekly, February 24th, 2005
According to recent research published in the Journal of Biological Chemistry, "Collagen IX is the prototype fibril-associated collagen with interruptions in triple helix. In human cartilage it covers collagen fibrils, but its putative cellular receptors have been unknown.
"The reverse transcription-PCR analysis of human fetal tissues suggested that based on their distribution all four collagen receptor integrins, namely alpha(1)beta(1), alpha(2)beta(1), alpha(10)beta(1), and alpha(11)beta(1), are possible receptors for collagen IX."
"Furthermore,"...
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Source: Blood Weekly (2005-02-24)
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