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Breast Cancer

Truck driver occupation linked to increased BRCA1/2 male breast cancer mutation

Published in Blood Weekly, March 3rd, 2005

Occupation as a truck driver is linked to an increase in the BRCA1/2 male breast cancer mutation.

"The association of male breast cancer (MBC) with a positive breast cancer (BC) family history and with BRCA1/2 germ-line mutations points to a genetic component; a relationship with occupation has also been reported.

"Recently, we identified pathogenetic BRCA1/2 mutations in a population-based series of Italian MBC patients: here in, we investigated interactions between a carrier status for BRCA1/2 mutations and occupation using a case-case design and estimating case-only odds ratios (CORs)," scientists in Italy report.

According to...

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