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Blood Substitute

Blood substitute does not influence coagulation at relevant concentrations

Published in Blood Weekly, March 3rd, 2005

A colloidal blood substitute does not influence coagulation at relevant concentrations.

According to recent research from South Africa, "Hemopure is a new colloidal blood substitute that may influence coagulation. We designed this study to examine the influence of this product on in vitro coagulation of whole blood by using the thrombelastograph (TEG). Blood samples from 20 volunteers were obtained."

"Hemopure was added to blood samples to obtain 0.5, 1, and 2 g/dL mixtures of Hemopure in blood. Control consisted of an undiluted sample and, for comparison, two samples diluted with volumes of lactated Ringer's solution (LR) equivalent to the two...

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