Hemodilution
Albumin-heme improves circulatory volume following hemorrhage
Published in Blood Weekly, March 3rd, 2005
According to a study from Japan, "Recombinant human serum albumin (rHSA) incorporating the synthetic heme 'albumin-heme' is an oxygen-carrying plasma protein that has the potential to be a red blood cell substitute.
"The physiological responses to a 30% exchange transfusion with two types of albumin-heme (rHSA-FecycP, rHSA-FepivP) solutions after 70% isovolemic hemodilution with 5 g/dL rHSA were investigated using anesthetized rats. The circulation parameters, blood parameters, renal cortical oxygen pressure (pO2 ), and muscle tissue pO2 were carefully monitored for...
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Source: Blood Weekly (2005-03-03)
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