Published in Blood Weekly, March 10th, 2005
Study 1: Reengineered stromal cells support the proliferation of naive T cells.
According to a study from Italy, "T cell-depleted allogeneic stem cell transplantation is associated with delayed immunological reconstitution. Bone marrow stroma and interleukin 7 (IL-7) regulate homeostasis of T lymphocytes. We engineered human stromal cells with a retroviral vector containing the IL-7 gene and studied in vitro effects on T cells."
"Human stromal cells were successfully transduced and generated a layer that was morphologically and...
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