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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . March 17th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Bone Formation Markers - EDA+/EDB+ fibronectin splice variants are markers for bone formation

Fetal Stem Cell Research - Fetal bone cells potential use for tissue engineering

Hematology - Gene therapy offers hope for correcting hemophilia

Stem Cell Transplantation - Adrenomedullin and endothelin-1 stimulate cord blood stem cell expansion

Tissue Engineering - MSCs immunoprivileged & potentially useful for HLA-incompatible transplantation

Abdominal Aortic Aneurysms - Company applauds the U.S. Preventive Services for recommending AAA screening

Alternative Medicine - Treatment with electroacupuncture reduced duration of arrhythmia and mortality

Amyotrophic Lateral Sclerosis - Details discovered on how human stem cells become nerve cells

Atherosclerosis - Reduced uptake of alpha-tocopherol may be relevant to atherogenesis

Bacteriology - Some Staphylococcus aureus clones more virulent than others

Bifidobacterium Bifidum - Monomeric aspartate racemase Bifidobacterium bifidum molecularly analyzed

Transplant Medicine - Researchers' work adds to transplant medicine body of knowledge

Biomedical Research - SCNT stem cell research could benefit over 500,000 Missourians, study shows

Biotechnology - Chromatin immunoprecipitation assay modifications improve its success/utility

Bladder Cancer - Dietary carotenoids and genetic instability modify bladder cancer risk

Bladder Cancer - HER3 and HER4 expression associated with better survival in bladder cancer

Blood Supply - NY/NJ blood supply down to crisis proportions

Brain Aneurysms - Committee: Coil embolization treatment safe and effective

Breast Cancer - Estrogen receptor mutations identified in cancer & psychiatric disease

Breast Cancer - Polymorphisms in MMP genes can influence breast cancer phenotype

Business Update - Global Med Technologies retains The Investor Relations Group

Business Update - HemoGenix announces the release of the OxyFLOW research kit

Business Update - Personalized medicine provider gets CAP accreditation

Cancer Stem Cells - Cancer stem cells isolated from adult glioblastoma multiforme

Cancer Therapy - Reports add new data to cancer therapy research

Cardiovascular Research - Inflammatory biomarkers could not explain the role of tHcy in heart disease

Coagulation Therapy - New anticoagulants target specific enzymes or steps in the coagulation pathway

Colon Cancer - Age-related ERRP loss in aging colon is potential risk factor for colon cancer

Coronary Artery Bypass - Benefits of off-pump bypass surgery elucidated

Coronary Heart Disease - Three weeks of stationary cardiac rehabilitation improves plasma lipids levels

Diagnostics - Elispot assay optimized to detect cytomegalovirus-specific CD8+ T lymphocytes

Diagnostics - HPLC detects depression-linked markers in hepatitis C patients on interferon

Diagnostics - Joey Diagnostic device that tests cord blood of newborn ready for use

Diagnostics - Latex agglutination test diagnoses visceral leishmaniasis in HIV co-infection

Diagnotics - PCR-based method accurately detects thalassemia mutations in cord blood

Drug Development - Virostat evaluated in phase II trial for hepatitis C

Drug Development - p73 induction after DNA damage is regulated by Chk1 and Chk2

Embryonic Stem Cell Research - Ethical debates impede progress of embryonic stem cell research

Embryonic Stem Cell Research - Human feeder cells support maintenance of embryonic stem cells in culture

Endocrinology - ELISA assay separately measures plasma levels of acylated and desacyl ghrelin

Enterococcus Faecalis - Gentamicin-resistant Enterococcus faecalis strains characterized

Epidemiology - Water is a major vehicle for Cryptosporidium transmission

Epidemiology - Waterborne transmissions increasing for Toxoplasma gondi

Factor XI Deficiency - Bleeding disorder reviewed

Fibrocytes - Peripheral blood fibrocytes contribute to the formation of the avian spleen

Finance - Biopharmaceutical company reports year-end and fourth quarter results

Finance - Company reports 2004 income of $217.2 million, $2.11 per share

Finance - Instrumentation company reports record profits

Finance - Stem-cell banking company announces 62% revenue increase

Genotoxicity - Multiple factors contribute to mechanism of particulate matter genotoxicity

HIV/AIDS Behavior - Theory-based approach identifies job-seeking behavior of persons with HIV/AIDS

HIV/AIDS Cognition - HIV+ substance users fair worse on cognitive impulse test than HIV- users

HIV/AIDS Diagnostics - BM biopsy not sensitive as diagnostic tool in AIDS patients with fever

HIV/AIDS Diagnostics - Neurospychiatric symptoms from efavirenz difficult to diagnose in HIV infection

HIV/AIDS Diagnostics - Rapid and standard HIV Ab ELISAs negatively affected by HIV-indeterminates

HIV/AIDS Disease Progression - Anti-NTM antibodies is a useful prognostic marker for HIV disease

HIV/AIDS Drug Resistance - Certain HIV-1 resistance-associated mutations are highly stable

HIV/AIDS Drug Resistance - NRTIs may have continued anti-HIV-1 activity despite presence of resistance

HIV/AIDS Epidemiology - HIV-1 genetically diverse in rural eastern Cameroon

HIV/AIDS Epidemiology - Homeless in San Francisco HIV seroconversion incidence/risk factors estimated

HIV/AIDS Pathogenesis - CD27 expression promotes long-term survival of CD8+ cells in HIV-infection

HIV/AIDS Pathogenesis - HIV-1 Nef does not significantly affect viral infectivity in target cells

HIV/AIDS Pathogenesis - HIV-1 Nef promotes physical interaction between endogenous AP-1 and MHC-I

HIV/AIDS Pathogenesis - Oligomerization required for HIV-1 Nef-induced Hck activation

HIV/AIDS Pathogenesis - Perlecan mediates cellular uptake of HIV-1 Tat

HIV/AIDS Pathogenesis - Research add new data to HIV/AIDS pathogenesis body of knowledge

HIV/AIDS Prevention - Antenatal couple counseling prevents HIV-1 transmission

HIV/AIDS Prevention - Antiretrovirals to prevent vertical transmission protects against infant anemia

HIV/AIDS Prevention - HIV prophylaxis should be offered to children following sexual assault

HIV/AIDS Prognosis - HIV genotype/virtual phenotype predicts treatment outcome same as real phenotype

HIV/AIDS Research - Cell lines with an integrated luciferase gene determine HIV-1 infectivity

HIV/AIDS Research - Closing of the fingers domain generates motor forces in HIV RT

HIV/AIDS Research - Researchers' data advance HIV/AIDS research

HIV/AIDS Therapy - Findings describe new data in HIV/AIDS therapy research

HIV/AIDS Therapy - Large difference in cervicovaginal penetration among antiretroviral agents

HIV/AIDS Therapy - Nelfinavir induces adipocyte necrosis by oxidative stress

HIV/AIDS Therapy - Stavudine plus didanosine associated with decreased mitochondrial mass

HIV/AIDS-Associated Neuropathy - CSP latency is first sign of neuropathy spread to upper limb in HIV patients

Hemodialysis - Ideal dry weight estimated by ECG improved quality of life for dialysis patients

Hemodialysis - Slime factor positivity in nasal coagulase negative staphylococci determined

Hepatitis C - Association noted between certain nonliver cancers and hepatitis C in Sweden

Herpesvirus - Researchers report details of new studies and findings in the area of herpesvirus

Hypertension - Positive results reported for CYT006-AngQb treatment of hypertension

Hypertension - Rise in plasma ET-1 was more pronounced in dialysis patients with hypertension

Immunology - Selective differences in circulating APCs between neonates and adults

Information Technology - Software enables access to blood donor information

Leukemia - AML1-ETO C-terminal NcoR/SMRT-interacting region deletion induces leukemia

Leukemia - Findings in leukemia provide new insights

Leukemia - Gamida-Cell and Teva to develop and commercialize StemEx for leukemia

Leukemia - Genome-wide mouse study yields link to human leukemia

Leukemia - Plant derivative attacks the roots of leukemia

Leukemia - Protein that helps stem cells may be key to poor leukemia prognosis

Locust Plague Monitoring - MODIS data monitors oriental migratory locust plague

Lung Cancer Pathogenesis - Immortalized bronchial epithelial cells useful to study lung cancer pathogenesis

Malaria -  Plasmodium parasite is a "new" challenge for insect innate immunity

Malaria - Improved detection and response is useful tool for malaria epidemic planning

Melanoma - Genes identified expressing elevated melanoma metastatic variants

Myelodysplastic Syndromes - Clinical data from initial REVLIMID study reported in journal

Nanotechnology - Biofunctionalized nanoparticles used to probe pathogenic bacteria

Neural Stem Cell Transplantation - Injected neural stem cells migrate to ischemic brain and undergo proliferation

Neural Stem Cell Transplantation - Neural stem cell transplantation remyelinates demyelinated CNS axons

Neural Stem Cells Research - Radial glia give rise to adult neural stem cells in subventricular zone

Neurodegeneration - Quercetin protects against oxidative stress-induced neurodegeneration

Non-Hodgkin Lymphoma - Findings in non-hodgkin lymphoma provide new insights

Oncology - CagA structure variability may explain H. pylori-related diseases

Oncology - Vascular leukocytes support tumor vessel growth

Organ Transplantation - ED physician must consider infections when evaluating transplant recipients

Pancreatic Cancer - IFN-gamma polymorphisms correlate with duration of survival in pancreatic cancer

Personnel - Diagnostics company appoints vice president of marketing

Physiology - Human lymphocyte activation analyzed, regulated expression of ATPase pump shown

Polycystic Ovary Syndrome - WBC count in PCOS correlates with homeostasis model assessment values

Preimplantation Genetic Diagnosis - PGD is a reproductive option for carriers of hemophilia

Primary Hyperaldosteronism - Utility of aldosterone-renin ratio in diagnosis clarified

Prostate Cancer - HOXB13 suppresses growth of prostate cancer cells

SARS Outbreaks - Research in SARS ouTBreaks provides new insights

Sepsis Therapy - Utility of high-volume hemofiltration reviewed

Sickle Cell Disease - New bone marrow model could help people with blood disorder

Stem Cell Research - Caspase-3 crucial for osteogenic differentiation of BM stromal stem cells

Stem Cell Research - Clonal type I IFN-producing/DC precursors contained in lymphoid/myeloid SCs

Stem Cell Research - Ink4a/ARF links senescence and aging

Stem Cell Research - Letter of Intent filed with U.S. NIH for stem cell research center grant

Stem Cell Research - Telomerase activity/length measured in proliferating mesenchymal stem cells

Stem Cell Research - Young blood revives aging muscles, Stanford researchers find

Stem Cell Transplantation - Findings advance knowledge in stem cell transplantation research

Stem Cell Transplantation - Several factors account for different transplant rates in Eastern/Western Europe

Stroke - Study shows hemophilia drug helps bleeding stroke patients

Testosterone-Producing Cells - Progenitor cells of testosterone-producing Leydig cells revealed

Thrombocytopenia - Thrombocytopenia studied, therapeutic approach for minibody agonist shown

Thyrotoxic Periodic Paralysis - KCl dose should be small to avoid rebound hyperkalemia in TPP patients

Tissue Engineering - Mesenchymal stem cells integrate/migrate in colonized contructs in murine model

Tissue Engineering - Osteochondritis dissecans of talus treated with tissue-engineered cartilage

Tissue Engineering - Silk fibroin matrices suitable for wound dressing/tissue engineering scaffolds

Tissue Engineering - Various scaffold fabrication methods for tissue engineering

Toxicology - Blood lead predicts homocysteine levels in older adults

Transplant Medicine - Renal data shows California hospital has best kidney transplant success rate

Transplant Medicine - Research add new data to transplant medicine body of knowledge

Umbilical Cord Blood Transplantation - Umbilical cord stromal cells promising for cell-based therapies

Virology - Research in virology provides new insights

Water Treatment - Coagulation pretreatment influences protozoan cyst removal from water

Wilms Tumor - Adult nephroblastoma patients may carry WT1 germline mutations

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