Stem Cell Transplantation
Adrenomedullin and endothelin-1 stimulate cord blood stem cell expansion
Published in Blood Weekly, March 17th, 2005
According to a study from Italy, "The improvement of techniques for in vitro expansion of cord blood (CB) hematopoietic stem cells (SCs) is, at present, one main task of tissue engineering.
"Hence, we investigated whether endothelin-1 (ET-1) and adrenomedullin (AM), two regulatory peptides exerting growth promoting action on several cell systems, favor the in vitro expansion of CB SCs in liquid culture."
"CB hematopoietic cell middle-term expansion was carried out in a stroma-free liquid culture medium in the presence of ET-1, AM and...
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Source: Blood Weekly (2005-03-17)
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