Susan Hasty, Publisher
Table of Contents . . . March 24th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Blood Banking - Rehydrated RBCs sufficiently deformable for normal microcirculation transit
Blood Safety - NAT testing finds hepatitis B in a blood donor with unapparent acute infection
Bone Marrow Transplantation - Distinct recovery phases of innate cellular-mediated immunity after BMT
Bone Marrow Transplantation - Flow cytometry/microbead platform evaluates immune reconstitution after BMT
Tissue Engineering - Organoid culture in elliptic hollow fibers develops hybrid artificial liver
Aspergillosis - EIA/qPCR used to diagnose invasive aspergillosis in high-risk patients
Bacterial Evolution - VNTRs appropriate evolutionary marker for studying bacterial transmission events
Biomedical Engineering - Sonic hedgehog gene enhanced tissue engineering stimulates bone formation
Blood Safety - 54-year-old woman dies after receiving wrong blood
Blood Safety - Patients accidentally infected with hepatitis C respond well to interferon
Blood Substitute - Enrollment complete in phase 2 clinical trial of hemoglobin-based oxygen carrier
HIV/AIDS Research - Findings advance knowledge in HIV/AIDS research
Business Update - Company announces entry into field of regenerative medicine
Business Update - Sentigen Holding Corp. Announces the Sale of Its Specialty Media Division
Cancer Therapy - Evotec OAI to provide process validation for phase III compound, AMD 3100
Cancer Therapy - Findings advance knowledge in cancer therapy research
Cardiac Cell Therapy - Review details clinical potential of stem cell sources for cardiac cell therapy
Cardiology - Tryptase is proangiogenic in the healing heart
Chronic Hepatitis C - Liver regeneration does not affect HCV recurrence after split liver transplant
Collaborations - Company signs research agreement with Detroit hospital to target ER care
Colon Cancer - Nondegraded total RNA extracted from colonocytes from normal/malignant tissue
Cryptococcus Diagnostics - RT-PCR assay detects and quantitates Cryptococcus neoformans
Drug Development - Modified heparin antagonizes angiogenesis without affecting coagulation
Drug Development - P3 and P4 moieties analyzed, novel binding of factor VIIa inhibitor revealed
Embryonic Research - Failure to degrade poly(ADP-ribose) causes early embryonic lethality
Enterotoxigenic Escherichia Coli - Phenotypes determined for ETEC associated with early childhood diarrhea
Escherichia Coli 0157 Diagnostics - IS1203 PCR rapidly genotypes Shiga toxin-producing Escherichia coli O157
Finance - Developer, manufacturer of human cell lines reports 2004 results
Finance - HIF-focused company completes equity financing
Finance - Maker of ultrasound-enhanced microcatheters raises $18M in series B financing
Finance - Pharmaceutical company hires banking firm to identify partners, investors
Gastroenterology - Cathepsin B blockade stops reperfusion-induced liver damage in steatotic livers
Gene Expression - Interleukin regulation of gene expression studied, role of adherence shown
HIV/AIDS Coinfection - Schistosoma mansoni/HIV-1 coinfection leads to CD4 cell reduction
HIV/AIDS Coinfection - CD4 counts higher in HIV-positive patients infected with Helicobacter pylori
HIV/AIDS Diagnostics - Real-time PCR rapidly discriminates between HIV-2 genotypes A and B
HIV/AIDS Drug Side Effects - Mitochondrial pathogenesis in AIDS due to NRTI-induced DNA polymerase inhibition
HIV/AIDS Encephalitis - Increased FKBP12 may explain vulnerability of basal ganglia to HIV infection
HIV/AIDS Mental Health - Substance P has role in pathophysiology of stress/depression in HIV infection
HIV/AIDS Neurology - CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults
HIV/AIDS Pathogenesis - Acute SIV brain infection leads to upregulation of IL6 ad IFN-regulated genes
HIV/AIDS Pathogenesis - Amyloid precursor protein may facilitate monocyte entry into brain
HIV/AIDS Pathogenesis - Conformational flexibility retained in HIV-1 Rev-RNA complexes
HIV/AIDS Pathogenesis - HIV-specific CTLs from long-term survivors select a unique T cell receptor
HIV/AIDS Pathogenesis - LEDGF/p75 prevents proteasomal degradation of HIV-1 integrase
HIV/AIDS Pathogenesis - MCP-1-2578G allele associated with elevated MCP-1 in cerebrospinal fluid
HIV/AIDS Pathogenesis - Macrophage-secreted MMP 9 is down-regulated following HIV-1 infection
HIV/AIDS Pathogenesis - Soluble toll-like receptor 2 associated with progression of HIV infection
HIV/AIDS Pathogenesis - Ubiquitinated histone H1B is a cofactor to HIV-1 resistance factor
HIV/AIDS Pathogenesis - Urokinase plasminogen activator receptor important in HIV-associated dementia
HIV/AIDS Pediatrics - HAART should be initiated in symptomatic children aged 12 months or older
HIV/AIDS Prevention - Fear of test result and stigmatization are barriers to HIV testing in Bali
HIV/AIDS Research - Data advance knowledge in HIV/AIDS research
HIV/AIDS Research - Tissue culture model analyzes macrophage activation in the brain
HIV/AIDS Therapy - Antiretroviral enfuvirtide is not an inhibitor of p450 cytochrome
HIV/AIDS Therapy - Enfuvirtide improves health-related quality of life in HIV-infected patients
HIV/AIDS Therapy - HAART adherence is the most relevant factor for virological success
HIV/AIDS Therapy - HPLC/UV method suitable for pharmacokinetics of abacavir in plasma
HIV/AIDS Therapy - Molecular basis determined for GLUT4 inhibition by protease inhibitors
HIV/AIDS Therapy - Protease inhibitors impair glucose-stimulated insulin secretion from beta cells
HIV/AIDS Therapy - Studies add new findings to HIV/AIDS therapy body of knowledge
HIV/AIDS-Associated Dementia - Antibody markers identified in HIV-associated dementia
HIV/AIDS-Associated Dementia - Blood-brain barrier compromise has role in pathogenesis of HIV-related dementia
HIV/AIDS-Associated Dementia - HIV dementia risk is associated with apolipoprotein E4 in older persons
HIV/AIDS-Associated Dementia - Oxidative stress markers increased in actively progressive HIV dementia
HIV/AIDS-Associated Infection - Severe respiratory disease necessitating hospitalization decreased in HAART era
HIV/AIDS-Related Dementia - Brain water diffusion contributes to cognitive deficits in HIV infection
HIV/AIDS-Related Dementia - CD14+ macrophage hybrid phenotype circulates in persons with high HIV viral load
HIV/AIDS-Related Dementia - HIV dementia is an evolving disease
HIV/AIDS-Related Lipodystrophy - F-18-fluorodeoxyglucose PET visualizes lipodystrophy in HIV-infected patients
Hematology - Cells secrete interleukin-1 alpha after intramarrow gene transfer
Hematology - Immature dendritic cells help CD40 ligand regress established myeloma
Hematology - Myelofibrosis with myeloid metaplasia formation and VEGF levels often parallel
Hematology - New findings in the area of hematology described
Hematology - Zebrafish model transferrin receptor 1 function in erythroid cells
Hematopoiesis - C/EBPalpha is essential for granulocyte development/regulates HSC activity
Hematopoiesis - Enhanced self-renewal of HSC mediated by polycomb gene product Bmi-1
Hematopoiesis - NF-kappaB prevents apoptosis at multiple steps of hematopoiesis by removing ROS
Hemodialysis - Access monitoring does not improve outcome
Information Technology - Technology company releases donor management system for review
Interleukins - Normal platelets possess the soluble form of IL-6 receptor
Ischemia/Reperfusion - Study investigated effects of sildenatil citrate on ischemia reperfusion injury
Kaposi Sarcoma-Associated Herpesvirus - New research in the area of kaposi sarcoma-associated herpesvirus detailed
Leishmaniasis - Promising visceral leishmaniasis treatments must translate into actual therapy
Leptospirosis - Percutaneous exposure results in laboratory-acquired leptospirosis
Licensing - Pharmaceutical firm acquires license to endothelinB agonists for chemo delivery
Liver Transplantation - Adult living donor liver grafts offer a viable option to transplant candidates
Malaria - Malaria morbidity in children increases as transmission intensity decreases
Malaria - Malaria still reduced in areas after withdrawal of deltamethrin spray
Malaria Diagnostics - Four plasmodium species detected in blood by real-time PCR
Medical Devices - Self-calibrating nanoliter viscometers developed
Mergers & Acquisitions - Chemicon International acquires assets of Specialty Media
Metamorphosis - Red blood cells studied, low-temperature transcriptional arrest clarified
Microbial Identification - Multispacer typing useful for strain genotyping during outbreaks/bioterrorism
Microbial Resistance - Beta-lactam susceptibilities evaluated against Enterobacteriaceae isolates
Microbial Resistance - In France, ESBL-producing S. enterica strains emerging in chickens & humans
Mosquito-Borne Disease - Aircraft is the main vessel for mosquito entry into New Zealand
Mycobacterial Infection - New mycobacaterial species found in sputum of patient with hemoptoic pneumonia
Mycobacterium Abscessus - Inability to type M. abscessus by PFGE assoc. with single clone of organism
Mycobacterium Xenopi Infection - Mycobacterium xenopi infection developed following heart transplantation
Myeloma - "Smart" immune cells kill more cancer
Myocardial Infarction - Matrix-embedded marrow cells generate new vessels in ischemic hearts
Natural Products - San-Huang-Xie-Xin-Tang studied, effect on hypotension and inflammation shown
Neuroscience - Transduced adult neural stem cells thrive after inner ear transplantation
Personnel - Biotechnology company appoints president of the board
Personnel - Stem cell technology company appoints new non-executive cochairman
Plasma Collection - Haemonetics inks supply contract for plasma collection products
Platelets - Sildenafil studied, effect on human platelet secretory function clarified
Prenatal Genetic Diagnosis - Alternative screening protocol for blood diseases in pregnancy described
Pseudomonas Aeruginosa - Pseudomonas aeruginosa is non-clonal but has an epidemic population
Retroviral Infection - Ini1/hSNF5 is dispensable for retrovirus-induced cytoplasmic accumulation of PML
Reverse Transcriptase - AZT 5'-triphosphate mimics inhibit HIV reverse transcriptase
SARS Coronavirus - Chronological evolution of Ab levels determined after SARS coronavirus infection
SARS Coronavirus - RT-PCR distinguishes SARS coronavirus from other respiratory tract infections
Sickle Cell Disease - Enrollment initiated for phase III trial of ICA-17043 in sickle cell disease
Space Travel - Nanobacterial infections important during space travel
Stem Cell Research - CD38 expressed in myeloblast nuclei during RA-induced differentiation
Stem Cell Research - CTGF regulated by Wnt and BMP signaling in MSC osteoblast differentiation
Stem Cell Research - Cultured tooth papilla cells induce hair follicle regeneration and fiber growth
Stem Cell Research - Follicular epithelium and skin epidermis originates from the amnion
Stem Cell Research - Gene-corrected stem cells can help patients with cystic fibrosis
Stem Cell Research - MSCs isolated from BM and fetal liver can form a hematopoietic microenvironment
Stem Cell Research - Not all leukemic oncogenes transform committed SCs lacking self-renewal capacity
Stem Cell Research - PTH/PTHrP signaling is major regulator of bone marrow ontogeny
Stem Cell Research - Steroid hormones control differentiation of ESCs into various cell types
Stem Cell Transplantation - Alternate hemibody irradiation + HD chemotherapy treats hematological malignancy
Stem Cell Transplantation - Five-year survival >80% after HSCT with matched unrelated donors
Stem Cell Transplantation - Reconstitution of CMV-specific CD8+ T cells delayed after SCT
Stem Cells - Study finds hematopoietic stem cells depend on a single protein Mcl-1
Streptococcal Equi Diagnostics - Multiplex PCR differentiates closely related streptococcal species
Stroke - Drug helps bleeding stroke patients
Tick-Borne Virus - Tick-borne viruses in Europe are potential agents of bioterrorism
Transplant Medicine - Diabetes increases mortality in HCV-infected patients awaiting renal transplant
Transplant Medicine - New findings in transplant medicine described
Tuberculosis - M. tuberculosis lineage with low IS6110 copy numbers clonally expanded
Tuberculosis - Genotypic/phenotypic heterogeneity among M. tuberculosis isolates determined
Umbilical Cord Blood Transplantation - CBT treats case of EBV-related lymphoproliferative disease
Urea Cycle Disorder - Pharmaceutical company obtains FDA approval of treatment for urea cycle disorder
Vancomycin-Resistant Enterococcus - Esp/vancomycin resistance may contribute to clonal enterococcal dissemination
Vibrio Cholerae - Possible source of V. cholerae outbreak is effluent from ships or poachers
Virology - Research add new data to virology body of knowledge
West Nile Virus - West Nile virus is an emerging arbovirus
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