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Tuberculosis

 M. tuberculosis lineage with low IS6110 copy numbers clonally expanded

Published in Blood Weekly, March 24th, 2005

A Mycobacterium tuberculosis lineage with low IS6110 copy numbers was clonally expanded.

According to recently published research from South Africa, "Knowledge of the clonal expansion of Mycobacterium tuberculosis and accurate identification of predominant evolutionary lineages in this species remain limited, especially with regard to low-IS6110-copy-number strains.

"In this study, 170 M. tuberculosis isolates with {{<=}}6 IS6110 insertions identified in Cape Town, South Africa, were characterized by principal genetic grouping, restriction fragment length polymorphism analysis, spoligotyping, IS6110 insertion site mapping, and...

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