HIV/AIDS Research
Data advance knowledge in HIV/AIDS research
Published in Blood Weekly, March 24th, 2005
Study 1: Small interfering RNA targeted to the HIV-1 primer binding site can inhibit virus replication.
According to recently published research in the journal Virology, "The initiation of HIV-1 reverse transcription occurs at an 18-nucleotide sequence in the viral genome designated as the primer binding site (PBS), which is complementary to the 3' terminal nucleotides of tRNALys,3.
"Since the PBS is highly conserved among all infectious HIV-1, it represents an attractive target for the development of new therapeutics to inhibit...
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Source: Blood Weekly (2005-03-24)
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