Susan Hasty, Publisher
Table of Contents . . . April 7th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Bioartificial Liver - Bioreactor developed that supports bioartificial liver
Embryonic Stem Cell Research - Repository stores embryonic stem cell lines with genetic disorders
Stem Cell Transplantation - Chronic GVHD risk increased in patients with HLA class I mismatched donors
Stem Cell Transplantation - High plasmacytoid dendritic cell recovery improves overall survival after ASCT
Tissue Engineering - Hyaluronan gels useful for tissue engineering of aortic heart valves
Acinetobacter Infection - Risk factors identified for multidrug-resistant A. baumannii infection
Acute Myeloid Leukemia - Ceplene receives orphan drug designation in Europe for AML
Air Monitoring - PCR method quantifies A. fumigatus conidia from environmental air samples
Allergy and Immunology - Eosinophils in human blood stimulate angiogenesis
Amyloidosis - Medicare expands coverage for stem cell transplantation
Anemia - Positive data for phase I study of anemia treatment announced
Oncology - Research in oncology provides new insights
Angiology - Biodegradable implants containing factor XIII stimulate vessel growth in rats
Antimicrobial Resistance - Carbapenem resistance is emerging in strains worldwide
Avian Influenza - Cross-impact analysis predicts mutation trends in influenza A
Bioartificial Liver - Collagen/chitosan/heparin improves hepatic tissue engineering biocompatibility
Biomedical Engineering - Collagen films support osteoblast activity and bone formation
Bone Marrow Research - Bone marrow cells engraft within epidermis and proliferate without cell fusion
Bone Marrow Transplant - Monitoring of TCR-Vbeta complexity may help predict prognosis of GVHD after BMT
Business & Finance - Biopharma company announces financial results
Business Update - Contract signed for leukocyte reduction filters
Cancer Therapy - Dose optimization enables rapamycin to suppress tumor angiogenesis
Cardiovascular Research - Platelet inhibitor demonstrates consistent inhibition of platelet aggregation
Cholera Monitoring - Monitoring environment and cholera presence predicts diarrhea epidemics
Chronic Liver Disease - Patients with bleeding disorders can safely undergo transjugular liver biopsy
Coagulation Therapy - Protein C anticoagulant activity examined, role of cholesterol revealed
Coagulation Therapy - Study finds self-testing a reliable alternative to laboratory INR monitoring
Collaborations - Long-term contract signed for plasma products
Cowpox - Cowpox virus infection associated with streptococcal septicemia
Crimean-Congo Hemorrhagic Fever - ELISA method used to diagnose Crimean-Congo hemorrhagic fever
Cystic Fibrosis - Persistent environmental reservoirs of P. aeruginosa not found in CF center
Deep Vein Thrombosis - First patient recruited in ThromboView phase II North American clinical trials
Dengue Hemorrhagic Fever - Dengue hemorrhagic fever increasing among children in northern Brazil
Diabetes Type 1 - Diabetes type 1 outbreak earlier in immigrants' children born in Italy
Diagnostics - Studies add new findings to diagnostics body of knowledge
Diarrheal Illness - Hygiene interventions identified to reduce diarrhea in less developed countries
Drug Development - Company exercises option for rights to blood platelet modification technology
Drug Development - Hematide demonstrates ability to stimulate production of red blood cells
Embryonic Stem Cell Research - Cell-surface marker found on embryonic hepatoblasts
Embryonic Stem Cell Research - Embryonic stem cell differentiation evaluated in different culture conditions
Embryonic Stem Cell Research - Enforced PU.1 expression rescues osteoclastogenesis from ESCs lacking Tal-1
Embryonic Stem Cell Research - Stably transfected ESC clones maintain self-renewal and pluripotency
Environmental Health - Northern American maternal blood monitoring program established
Exercise and Nutrition - Exercise and diet have roles in prevention of chronic disease
Finance - Newborn stem-cell bank reports record growth in revenue
Finance - Stem cell-focused biotech company announces Q4, year end 2004 financial results
Food Contamination - Continuous education assures good food hygiene on merchant ships
Gallbladder Cancer - Early gallbladder cancer showed no interference with liver transplantation
Genetics & Genomics - IS1- or IS10- activated AcrEF efflux pump may relay AcrAB in serovar Typhimurium
Genomic Expression - Cytokine allele frequencies differ between racial and ethnic groups
HIV/AIDS Drug Development - Anti-HIV-1 compounds separated via capillary zone electrophoresis
HIV/AIDS Drug Development - PNA-transportan conjugate targeted to HIV-1 TAR is antiviral and virucidal
HIV/AIDS Drug Development - Plant extracts have anti-HIV activity
HIV/AIDS Drug Discovery - HIV-1 integrase inhibitors identified using 3D pharmacophore-guided database
HIV/AIDS Drug Resistance - Drug-resistant HIV-1 genotypes detected only in subjects infected after 2000
HIV/AIDS Drug Resistance - HIV-1 Vif changes associated with development of protease inhibitor resistance
HIV/AIDS Infection - Amphotericin-B reactivates latent HIV-1 infection
HIV/AIDS Lipodystrophy - VLDL elevation in early HAART therapy caused by impaired VLDL clearance
HIV/AIDS MALT Lymphoma - HIV+ MALT lymphoma remission induced by HAART alone
HIV/AIDS Pathogenesis - APOBEC3G polymorphisms not associated with HIV disease progression
HIV/AIDS Pathogenesis - C-terminal domain of HIV-1 integrase is a DNA-binding domain
HIV/AIDS Pathogenesis - Cytoplasmic tail slows HIV-1 Env folding from late prebundle into 6-helix bundle
HIV/AIDS Pathogenesis - Late stage R5 HIV-1 infection induces cytokine and CCR5 expression
HIV/AIDS Pathogenesis - M-tropic HIV-1 activation increases virus load in intestinal mucosa
HIV/AIDS Pathogenesis - Separate HIV Nef domains are required to affect MHC-1 and CD4 cells
HIV/AIDS Pathogenesis - Vpr enhances RANKL production via glucocorticoid receptor activity potentiation
HIV/AIDS Prevention - Appropriate HIV education maximizes acceptance of antenatal HIV antibody test
HIV/AIDS Prognosis - Survival prognostic factors differ by CD4 count among IVDU pre/post HAART era
HIV/AIDS Research - CD4+ cell response differs between HIV-exposed seronegative and HIV+ women
HIV/AIDS Research - MLV RNase H primer grip is an important determinant of fidelity of DNA synthesis
HIV/AIDS Research - Tat methylation by PRMT6 regulates HIV-1 gene expression
HIV/AIDS Screening - Urgent care center-based routine HIV screening programs are effective
HIV/AIDS Therapy - 20 mg/kg of amprenavir twice daily is safe for HIV-infected children
HIV/AIDS Therapy - C/EBP alpha reverses anti-adipogenic effects of nelfinavir
HIV/AIDS Therapy - Fixed conformation nucleoside analogs inhibit excision-proficient HIV-1 RT
HIV/AIDS Therapy - HAART leads to normalization of anti-Hsp70 and anti-cholesterol Ab levels
HIV/AIDS Therapy - IL-16 levels increase after structured intermittent HAART interruption
HIV/AIDS Therapy - Researchers' work adds to HIV/AIDS therapy body of knowledge
HIV/AIDS Therapy - Ritonavir does not inhibit calpain
HIV/AIDS-Associated Lipodystrophy - Subcutaneous fat loss not due to accelerated apoptosis in HIV lipodystrophy
Hematology - Angiogenic cytokines predict multiple myeloma progression
Hematology - Estrogen receptor gene expression deviates in human blood mononuclear cells
Hematology - Hemophilia A patients carry newly discovered missense FVIII gene mutations
Hematopoiesis - Recent findings in hematopoiesis provide new insights
Hemoglobin H Disease - Study tests efficiency of prenatal diagnostic tests for Hb Constant Spring
Henoch-Schonlein Purpura - Plasmapheresis can quickly resolve cerebral vasculitis in HSP patients
Human Papillomavirus - HPV-13 polymorphisms determined for HIV+ and women at risk for HIV infection
Immunology - TIM-3 gene polymorphism associated with atopic disease susceptibility
Immunosuppression - Mycophenolate mofetil delays hepatitis C recurrence after liver transplantation
Immunotherapy - Addition of GS doesn't enhance proapoptotic properties of MTX
Infection Control - Emerging Infections Program reduces response time to foodborne disease
Kaposi Sarcoma-Associated Herpesvirus - New findings in the area of kaposi sarcoma-associated herpesvirus described
Kidney Transplantation - Immunosuppressives reduce production of TNF alpha in NHBD kidneys
Legal Issues - Dialysis provider announces receipt of DOJ subpoena
Lymphoma - Epstein-Barr virus protein crucial to its role in blood cancers
Lymphoma - Investigation of CD3+/HLA-DR+ activated T cells may aid prognostics
Medical Devices - Study shows CYPHER stent associated with fewer blood clots at stent site
Multiple Sclerosis - Research suggests possible blood test for MS
Neural Embryonic Stem Cell Research - Neuronal differentiation achieved from cultured embryonic germ cells
Neural Stem Cell Research - Antibody microarray correlates cell phenotype with surface marker
Neural Stem Cell Research - Ginsenoside-Rd from Panax notoginseng enhances NSC astrocyte differentiation
Neural Stem Cell Research - NSCs from ESCs relieve symptomatic motor behavior in Parkinson disease model
Neural Stem Cell Research - RB & RB2/p130 genes have overlapping functions during early NSC differentiation
Neural Stem Cell Research - Repeated cytokine administration improves generation of dendritic cells
Neuroscience - Marrow stromal cells aid axonal regeneration after spinal cord injury
Norovirus - New data illuminates research in norovirus
Obstetrics - Tobacco smoke exposure increases resistance of umbilical blood flow
Oncology - New data illuminates research in oncology
Patents - Re-examination of two more PharmaStem cord blood stem cell patents requested
Patents - Stem cell instruments patent filed with U.S. patent office
Pathogenic Escherichia coli - E. coli O157:H7 survival on vegetables dependent on soil compost type
Personnel - Molecular biotechnology company names Tom Muenzberg COO
Personnel - Synthetic blood-focused biopharm company convenes medical advisory board
Physiology - Lipopeptide and peptidoglycan recognition studied, role of TLR6 clarified
Platelet Preparation - Rapid, one-step density gradient centrifugation method doesn't cause activation
Pneumocystis Infection - Neonatal lungs lack maturation factors for efficient cellular functioning
Pregnancy-Associated Malaria - IL-10+ T-cell upkeep in utero may affect APC function, infant's immune response
Product Licensing - Chemicon licenses Quantum Dot antibody reagent line
Recurrent Pregnancy Loss - Thrombophilia is a common cause of recurrent miscarriage syndrome
Respiratory Pathogen - Respiratory infection spread during air travel rarely occurs
SARS - Convalescent plasma therapy shortens hospitalization stays of SARS patients
SARS - Events reconstructed during SARS outbreak in February 2003 in Singapore
SARS - Nursing students more stressed than medical students during SARS outbreak
SARS - SARS seroprevalence rate is low in apparently healthy healthcare workers
SARS Coronavirus - Recombinant nucleocapsid protein-based assay detects anti-SARS-CoV IgG
SARS Prevention - Residents of Taiwan have increased "willingness to pay" to reduce SARS risk
Sepsis - Researchers report new pro-inflammatory role for anti-inflammatory enzyme
Sepsis - Risk of death from bloodstream infection greater in less severely ill
Sepsis - Study identified sepsis-induced changes in signal transduction pathways
Sporotrichosis - Sporotrichosis diagnosis may be confounded by Leishmania coinfection
Stem Cell Research - 4-Hydroxynonenal inhibits cell proliferation in fetal liver HSCs
Stem Cell Research - Bcl-2 reduced/Fas activated by SCF/KIT inhibition signaling in melanocyte SCs
Stem Cell Research - Cytokines reverse gamma-globin gene silencing in erythroid stem cells
Stem Cell Research - First derivation of human embryonic stem cells without exposure to cell feeders
Stem Cell Research - HSC homing is optimal when CXCR4 is incorporated in membrane lipid rafts
Stem Cell Research - Negative feedback loop controls SCF-KIT signaling pathway
Stem Cell Research - PBMCs and BM-derived HPC populations affected by acute soman poisoning
Stem Cell Research - Prominin-1/CD133 is expressed certain types of kidney cancer
Stem Cell Transplantation - Selected cytokine elimination does not alter allogeneic hematopoietic resistance
Stem-Cell Transplantation - Novel real-time PCR assay facilitates assessment of hematopoietic chimerism
Stroke - Awareness low among women, especially minorities
Systemic Lupus Erythematosus - Rituximab induced remission from hypercoagulable state associated with LA
Tissue Engineering - Articular chondrocytes express phenotype in a collagen-containing sponge
Tissue Engineering - Mechanical load promotes osteoblastic stem cell proliferation in Col I matrix
Tissue Engineering - tHA ceramics support cell attachment/proliferation/differentiation
Transplant Medicine - Autoimmune hepatitis forms following orthotopic liver transplantation
Transplant Medicine - Cyclosporine A-based combo therapy ineffective in preventing bone rejection
Transplant Medicine - Kidney transplant recipients need to exercise, monitor diet
Transplant Medicine - Livers from older donors may harm transplant recipients with hepatitis C
Transplant Medicine - Unexplained hepatitis in renal graft recipients may be caused by hepatitis E
Tuberculosis - String test as sensitive as sputum induction for TB detection in HIV infection
Tuberculosis and Candida Coinfection - Candida coinfection higher in tuberculosis patients with complications
Umbilical Cord Blood Research - TGF-beta1 suppresses CTL differentiation of cord blood naive CD8+ cells
Variant Creutzfeldt-Jakob Disease - Model choices for variant Creutzfeldt-Jakob disease projections are problematic
Venous Thromboembolism - VTE incidence calculated among Factor V Leiden carriers
Virology - Researchers' findings advance virology research
West Nile Virus - Interferon can cure cells of West Nile virus replicons
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