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Biomedical Engineering

Collagen films support osteoblast activity and bone formation

Published in Blood Weekly, April 7th, 2005

Collagen films support osteoblast activity and bone formation.

"This study aimed at guiding osteoblast cells from rat bone marrow on chemically modified and patterned collagen films to study the influence of pattern, on cell guidance. The films were stabilized using different treatment methods including crosslinking with carbodiimide (EDC) and glutaraldehyde, dehydrothermal treatment (DHT), and deposition of calcium phosphate on the collagen membrane," scientists writing in the journal Biomaterials report.

"Mesenchymal osteoprogenitor cells were differentiated into osteoblasts and cultured for 7 and 14 days on micropatterned (groove width: 27...

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