HIV/AIDS Pathogenesis
APOBEC3G polymorphisms not associated with HIV disease progression
Published in Blood Weekly, April 7th, 2005
According to published research from France, "CEM15 (or APOBEC3G) has recently been identified as an inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in vitro.
"To evaluate the impact of its genetic variations on the progression of acquired immunodeficiency syndrome (AIDS), we have performed an extensive genetic analysis of CEM15."
"We have sequenced CEM15 in a cohort of 327 HIV-1-seropositive patients with extreme disease progression phenotypes-either slow progression or rapid progression-and in 446 healthy control subjects, all of white...
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Source: Blood Weekly (2005-04-07)
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