Blood Weekly

Blood Cell Substitute - Liposomes encapsulating hemoglobin evaluated as a red blood cell substitute

Leukapheresis - SC mobilization influences CD34+ cell collection efficiency of leukapheresis

Stem Cell Transplantation - Cord blood better than haploidentical mobilized PBL for sustained engraftment

Tissue Engineering - Fiber-based tissue engineered scaffold designed for ligament replacement

Tissue Engineering - Hydrogel scaffold developed for cell adhesion and neural outgrowth

Adult T-Cell Leukemia - TSLC1 overexpression may be a molecular marker for acute-type ATL

Adverse Drug Reaction - Alemtuzumab immunotherapy reactivates hepatitis B virus infection

Antimicrobials - Findings advance knowledge in antimicrobials research

Antioxidant - Trolox enhances arsenic-mediated oxidative stress and apoptosis in APL

Apoptosis - Renal tubular cell apoptosis in glomerulosclerosis studied, factors clarified

Biomedical Engineering - Reengineered T cells acquire tumor-specific reactivity

Breast Cancer - Researchers detail new studies and findings in the area of breast cancer

Blood Donations - New York, New Jersey blood banks call for donors, stress critical shortage

Bone Marrow Transplantation - BMT successful in a patient with c-mpl-mutated CAMT from carrier donor

Brain Tumor - GRP78 expression correlates with favorable prognosis in neuroblastic tumors

Breast Cancer - Findings in breast cancer provide new insights

Breast Cancer - Interleukin-1beta induces IL-8 mRNA stabilization in breast cancer cells

Hematology - Recent findings in hematology described

Brucellosis - Plasmapheresis effective for infection-induced thrombotic microangiopathy

Cancer Immunotherapy - Inhibitory anti-FLT3 antibodies rebuff leukemic induction

Cancer Screening - Screen for leukemia resistance identified mutation pattern for PD166326

Cancer Therapy - Company reports 67% decrease in metastatic nodules with CTCE-9908

Cancer Therapy - Selective cytotoxicity and telomere damage in leukemia cells by using BIBR1532

Chemotaxis - UCB neutrophils yield same potency pattern for each ELR chemokine as adult cells

Chronic Myelocytic Leukemia - Company obtains orphan drug designation for c-Myb Antisense (LR3001) in CML

Complementary & Alternative Medicine - Honeybee products may help control tumor growth

Coronary Heart Disease - FVII haplotypes associated with cardiovascular risk factors in women

Creutzfeldt-Jakob Disease - FDA committee meeting focused on transmissible spongiform encephalopathies

Crimean-Congo Hemorrhagic Fever - M RNA of Balkan Crimean-Congo hemorrhagic fever virus strain characterized

DNA Research - Amine-coated microchip extracts DNA from whole blood

Diabetes Control - Microaggregates can be used as markers for thrombogenesis

Diagnostics - FDA approves COBAS AmpliScreen hepatitis C and HIV-1 tests

Diagnostics - Patent application filed for tissue blood flow measurement

Disease Associations - IgG antibodies to a beta-glycoprotein I domain studied, role in thrombosis shown

Embryonic Stem Cell Research - ESCs differentiate and myelinate after spinal cord transplantation

Embryonic Stem Cell Research - ESCs form organized/functional cardiac conduction system in vitro

Embryonic Stem Cell Research - FGF2 maintains ESC self-renewal by supporting extracellular matrix expression

Embryonic Stem Cell Research - Two-step culture system commits ESCs to epidural cell fate and differentiation

Epidemiology - Gastroenteritis outbreak associated with group A rotavirus/genogroup 1 sapovirus

Epidemiology - Quick action against re-emerging infectious diseases can avert outbreaks

Esophageal Cancer - HPTTG overexpression regulated by betacatenin/TCF pathway in esophageal cancer

Esophageal Cancer - p53 negative expression/p53R2 expression predicts CRT outcome in ESCC

Exercise - Researchers detail new studies and findings in the area of exercise

Finance - Maker of carbohydrate-based drugs closes on first tranche of $6.5M financing

Gastric Cancer - COX-2 correlates with F-box protein/Skp2 expression/prognosis in gastric cancer

Gene Activation - Tumor cell HLA-G gene activation involves cis-acting epigenetic changes

Genetic Research - Hematopoietic cells carrying the ribonuclease inhibitor gene hinder melanoma

Gossypol - (-)-Gossypol overcomes Bcl-2-mediated and Bcl-X-L-mediated apoptosis resistance

Graft-Versus-Host Disease - Antilymphocyte/thymocyte globulins reduce acute/chronic GvHD incidence/severity

HIV-2 Drug Mutation - Polymorphisms specific to HIV-2 identified in untreated patients

HIV/AIDS Biotechnology - EIA quantifies plasma and intracellular lopinavir in HIV-infected patients

HIV/AIDS Drug Action - Pharmacodynamics of CYP3A inactivation by HIV protease inhibitors determined

HIV/AIDS Drug Development - Interlocked dimeric parallel-stranded DNA quadruplex inhibits HIV-1 integrase

HIV/AIDS Drug Development - Recombinant cyanovirin-N developed for use as vaginal anti-HIV microbicide

HIV/AIDS Drug Development - Tuftsin-AZT inhibits HIV RT and augments host immunogenic cell function

HIV/AIDS Drug Interaction - Pharmacodynamics/pharmacokinetics help manage HIV-1 protease inhibitors

HIV/AIDS Drug Mechanism - Efavirenz enhances HIV-1 RT p66/p66 and p51/p51 homodimer interactions

HIV/AIDS Drug Therapy - Cellular mechanisms described for protease inhibitor-induced metabolic syndrome

HIV/AIDS Epidemiology - Low CCR5Delta32 frequency related to higher susceptibility to HIV-1 infection

HIV/AIDS Immune Activation - Use of HAART and other factors increase oxidative damage

HIV/AIDS Lipodystrophy - Metabolic and body composition changes vary according to HAART choice

HIV/AIDS Mortality - Net survival for HIV-infected children is 67% at 1 year and 39% at 5 years

HIV/AIDS Pathogenesis - CD8+ cells from HIV-1-infected patients lack functional recall memory to HIV gag

HIV/AIDS Pathogenesis - HIV-1 RRE heterogeneity important in viral pathogenesis and disease progression

HIV/AIDS Pathogenesis - HIV-1 Vpr inhibits maturation and activation of macrophages and dendritic cells

HIV/AIDS Pathogenesis - Modeling approach shows impact of HIV mutations on immune system

HIV/AIDS Prevention - Discrete-event simulation evaluates vertical transmission prevention strategies

HIV/AIDS Research - APOBEC3-edited HIV G->A hypermutants recovered by PCR method

HIV/AIDS Research - Advances in laboratory testing for HIV used to follow disease process

HIV/AIDS Research - Expression system provides hydrophobic peptide from HIV-1 p24 protein

HIV/AIDS Research - Redox status of cells regulated through complex and tightly regulated mechanism

HIV/AIDS Therapy - DNC not important in mtDNA depletion of anti-HIV dideoxynucleosides

HIV/AIDS Therapy - Protease inhibitor choice should maximize efficacy and patient tolerability

HIV/AIDS Therapy - Research add new data to HIV/AIDS therapy body of knowledge

HIV/AIDS-Related Cardiology - Metabolic changes occurring with HAART increase heart disease risk

HIV/AIDS-Related Diabetes - Apparent type 1 diabetes resolves in AIDS patient with CMV coinfection

HIV/AIDS-Related Disorder - TTP is responsive to plasma infusion therapy in HIV/AIDS

HIV/AIDS-Related Lipodystrophy - Buffalo hump in HIV-associated lipodystrophy associated with hyperinsulinemia

HIV/AIDS-Related Orthopedics - Sepsis not seen during 1-year follow-up of orthopedic implants in HIV infection