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Tissue Engineering

Fiber-based tissue engineered scaffold designed for ligament replacement

Published in Blood Weekly, April 14th, 2005

A fiber-based tissue-engineered scaffold was designed for ligament replacement.

"The anterior cruciate ligament (ACL) is the major intra-articular ligamentous structure of the knee, which functions as a joint stabilizer. It is the most commonly injured ligament of the knee, with over 150,000 ACL surgeries performed annually in the United States.

"Due to limitations associated with current grafts for ACL reconstruction, there is a significant demand for alternative graft systems," researchers in the United States report.

"We report here the development of a biodegradable, tissue-engineered ACL graft. Several design parameters...

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