Tissue Engineering
Human platelet supernatant can lead to chondrocyte dedifferentiation
Published in Blood Weekly, April 21st, 2005
"Articular cartilage is rich in collagen type II fibers and proteoglycans and is characterized by low cell density. Chondrocytes have specific nutritional requirements and therefore cannot be expanded in vitro without the risk of generating fibroblastoid cells expressing type I collagen. Therefore, various growth conditions were tested for cartilage tissue engineering," scientists in Finland report.
"Human platelets are a rich source of many growth factors including transforming growth factor-beta and platelet-derived growth factor. To investigate the effect of human platelet...
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Source: Blood Weekly (2005-04-21)
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