HIV/AIDS Epidemiology
HLA-A11 associated with CTL response against HIV-1 Nef in exposed persons
Published in Blood Weekly, April 21st, 2005
"HIV-1 is rapidly diversifying in African, Asian and Caucasoid populations, which in parallel display extensive polymorphism of genes encoding class I human leukocyte antigens (HLA). Immune responses mediated by HLA class I molecules are imprinting mutations in HIV-1, which in turn affects HIV-1 diversity.
"Intra- and inter-ethnic studies have shown reproducible HLA class I allele, haplotype and supertype associations with HIV-1 infection and the development of AIDS (HIV/AIDS)," wrote scientists in the journal Trends in...
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Source: Blood Weekly (2005-04-21)
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