HIV/AIDS Pathogenesis
Major coreceptors of HIV-2 variants identified from persons with/without viremia
Published in Blood Weekly, April 21st, 2005
According to a study from the Netherlands, "Human immunodeficiency virus type 2 (HIV-2) is generally considered capable of using a broad range of coreceptors. Since HIV-2 variants from individuals with nonprogressive infection were not studied previously, the possibility that broad coreceptor usage is a property of variants associated with progressive infection could not be excluded."
"To test this, we determined the coreceptor usage of 43 HIV-2 variants isolated from six long-term-infected individuals with undetectable plasma viremia. Using GHOST indicator...
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Source: Blood Weekly (2005-04-21)
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