Nocardia brasiliensis
Patients with N. brasiliensis actinomycetoma have type Th2 immune response
Published in Blood Weekly, April 21st, 2005
According to published research from Mexico, "IFN-gamma, TNF-alpha, IL-4, IL10 and IL-12 concentrations in the supernatant of peripheral blood mononuclear cell (PBMC) cultures and the in vitro proliferation of PBMC were studied in 25 patients with actinomycetoma caused by Nocardia brasiliensis and in 10 healthy controls from endemic zones."
"Cell cultures were stimulated by a N. brasiliensis crude cytoplasmic antigen (NB) and five semi-purified protein fractions (NB2, NB4, NB6, NB8, and NB10) separated by isoelectric.
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Source: Blood Weekly (2005-04-21)
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