Retinopathy
The nitric oxide pathway regulates stem cell-related retinal revascularization
Published in Blood Weekly, April 28th, 2005
"We have previously established a model inducing hematopoietic stem cell (HSC) production of circulating endothelial progenitor cells (EPCs) to revascularize ischemic injury in adult mouse retina. The unique vascular environment of the retina results in new blood vessel formation primarily from HSC-derived EPCs," according to researchers in the United States.
"Using mice deficient -/- in inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS), we show that vessel phenotype resulting from hemangioblast activity can be altered by modulation of...
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Source: Blood Weekly (2005-04-28)
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