Tissue Engineering
Bone scaffold demineralization influences osteogenic differentiation of BMSCs
Published in Blood Weekly, April 28th, 2005
"Mineralized and partially or fully demineralized biomaterials derived from bovine bone matrix were evaluated for their ability to support human bone marrow stromal cell (BMSC) osteogenic differentiation in vitro and bone-forming capacity in vivo in order to assess their potential use in clinical tissue-engineering strategies," scientists writing in the journal Biomaterials report.
"BMSCs were either seeded on bone-derived scaffolds and cocultured in direct cell-to-scaffold contact, allowing for the exposure of soluble and insoluble...
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Source: Blood Weekly (2005-04-28)
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