Susan Hasty, Publisher
Table of Contents . . . May 5th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Osteopetrosis - High peripheral blood SCs enable autologous backup before SCT for osteopetrosis
Stem Cell Transplantation - ABO incompatibility does not affect clinical outcome after APBSCT
Stem Cell Transplantation - Circulating DC subsets post-ASCT correlate with acute GVHD severity in children
Tissue Engineering - Bovine collagen constructs used to reconstruct full-thickness scalp defects
Acinetobacter Outbreaks - Acinetobacter baumannii nosocomial outbreak strain produces PER-1 ESBL
African Swine Fever - Invader assay adapted for African swine fever virus DNA detection
Androgen Receptor - Notch signaling mediator Hey1 is an androgen receptor corepressor
Antiviral Drug Development - Understanding viral life cycles crucial to exploit antiviral strategies
Apoptosis - Annexin A5 analyzed, downregulation of tissue factor expression revealed
Apoptosis - p53 has crucial role in signal transduction pathways of silica-induced apoptosis
Arthritis - Pharma co receives U.S. FDA clearance for injured tissue stem cell therapy trial
Bacille Calmette-Guerin Infection - PB/BM findings described in disseminated bacille Calmette-Guerin infection
Bacteriology - M. gastri cause of disseminated infection in children of same family
Bacteriology - PCR detects and quantitates benzoyl-CoA reductase genes from bacteria
Biomedical Engineering - Technological advances exploited to engineer cardiac tissue
Blood Supply - African American Pastors' Coalition partners to hold blood drives in Texas
Bone Marrow Transplantation - Early VRE infection post-BMT associated with rapid deteriorating clinical course
Breast Cancer - Ki67 breast cancer marker correlates with regulation of apoptosis-related genes
Breast Cancer - Methyl mercury influences growth-related signaling in breast cancer cells
Breast Cancer - Real-time PCR measures Epstein-Barr virus DNA in archival breast adenocarcinomas
Business Update - "Research use only" ETP assay now available
Business Update - CordLife opens banking facility in Hong Kong
Cancer Genetics & Genomics - Single-round PCR assay detects BCL2-IGH
Cancer Inhibitor - Leukemia inhibitory factor receptor characterized in goldfish
Cancer Prevention - Anthocyanidins from fruits and vegetables inhibit tumor cell growth
Cancer Therapy - Researchers' findings advance cancer therapy research
Cardiac Surgery - Autologous blood predonation with erythropoietin avoids homologous transfusion
Cardiac Surgery - Symptomatic cerebrovascular accidents are rare following the Fontan procedure
Cardiology - Octylguanidine protects against damage induced by ischemia-reperfusion
Chikungunya Virus - RT-PCR without RNA extraction detects/quantifies African Chikungunya viruses
Cholera Epidemics - Seasonal cholera epidemics inversely correlate with cholera phage prevalence
Chronic Myeloid Leukemia - Recent approaches to CML interrupt key signaling pathways activated by Bcr-Abl
Clinical Trials - Clot buster enters Phase II stroke trial
Collaborations - Curis announces second major collaboration
Colon Cancer - Curcumin inhibits colon cancer via PPARgamma activation
Colon Cancer - Gastrin promotes colon cancer via CCK-2 receptor-mediated COX-2 induction
Colon Cancer - Quercetin inhibits beta-catenin/Tcf signaling in colon cancer cells
Colorectal Cancer - n596 gene deletion causes hereditary nonpolyposis colorectal cancer
Contraceptive Microbicide - Contraceptive microbicide nonoxynol-9 has deleterious effects on endometrium
Cutaneous Tuberculosis - Tuberculosis verrucosa cutis results in fixed-flexion deformity of arm
Diagnostics - EPIX initiates phase II trial of EP-2104R for blood-clot detection using MRI
Diagnostics - Flow cytometry detects circulating endothelial cells and their progenitors
Diagnostics - PCR-RFLP discriminates Campylobacter jejuni strains
Diet & Nutrition - Elemental diet improves nutritional recovery from diarrhea/malnutrition
Drug Development - Biopharma company confirms scale up of Cascade technology for plasma proteins
Drug Development - Glycerophosphoinositols inhibit tumor cells from invading extracellular matrix
Embryonic Stem Cell Research - Embryonic stem cells generate airway epithelial tissue
Epidemiology - Multidrug-resistant A. baumannii outbreak confined to ICU and surgical ward
Epidemiology - Nosocomial outbreak investigation database developed
Epstein-Barr Virus - Epstein-Barr virus dUTPase upregulates the production of TNF-alpha
Finance - Automated instrument-reagent systems trigger record third quarter results
Gene Research - Genetic elements affect susceptibility to hemolytic uremic syndrome
HIV-2 Epidemiology - SIVsm strains isolated from Sierra Leone bush meat highly divergent from HIV-2
HIV/AIDS & Syphilis Coinfection - Seronegative syphilis in HIV patient tests positive by dark field examination
HIV/AIDS Diagnostics - Early response to antiretroviral treatment predicts long-term response
HIV/AIDS Diagnostics - NucliSens EasyQ correlates with Roche Amplicor in monitoring HIV-1 RNA in Africa
HIV/AIDS Diagnostics - Sensitive PCR estimates HIV-1 in CD4+ cells in patients responding to HAART
HIV/AIDS Drug Development - CCR5 antagonist suppresses replication/CPE in HIV-infected mouse model
HIV/AIDS Drug Interactions - Antiretrovirals often interact with medications for OIs and primary care
HIV/AIDS Drug Resistance - Recent findings in HIV/AIDS drug resistance described
HIV/AIDS Epidemic - Assay screens HIV-1 in epidemics characterized by mono/dual clade predominance
HIV/AIDS HAART - High blood lipids observed with PIs increase 10-year coronary risk
HIV/AIDS Healthcare - Treatment-seeking behavior same in HIV/AIDS orphans/nonorphans in Kampala
HIV/AIDS Pathogenesis - APOBEC3G antiviral function can dissociate from cytidine deaminase activity
HIV/AIDS Pathogenesis - HIV-1 catalytic core domain residues important for HIV-1 replication/integration
HIV/AIDS Pathogenesis - HIV-1 clade promoters strongly influence replication spatial/temporal dynamics
HIV/AIDS Pathogenesis - HIV-1-specific CD4+ cell turnover and activation increase upon viral rebound
HIV/AIDS Pathogenesis - POSH is essential for HIV-1 production
HIV/AIDS Pathogenesis - Unintegrated HIV-1 reservoir in recently infected resting CD4+ cells very labile
HIV/AIDS Pediatrics - Infants are increasingly exposed antiretrovirals even from conception
HIV/AIDS Research - "Preloaded" natural killer cells efficiently lyse HIV-infected target cells
HIV/AIDS Research - Quantitation of RT-PCR defective/ecotropic viruses in murine AIDS
HIV/AIDS Risk Behavior - Puerto Rican crack users in Puerto Rico have riskier sex than those in New York
HIV/AIDS Therapy - Lethal mutagenesis may be used to extinguish HIV infection
HIV/AIDS Therapy - NNRTIs and RNase H inhibitors given in same HAART regimen may be beneficial
HIV/AIDS Therapy - Older antiretroviral strategies show renewed interest
HIV/AIDS Vaccine - Segments of consecutive AA residues of HIV gp120 proposed as vaccine candidates
HIV/AIDS-Associated Emphysema - AIDS-associated emphysema due in part to HIV-1 infection of alveolar macrophages
HIV/AIDS-Epidemiology - High HSV-2/HHV-8 in remote area belies behavior that may facilitate HIV spread
HIV/AIDS-Related Hodgkin Lymphoma - LMP-1 deletion mutants highly associated with HIV-related Hodgkin's lymphoma
Helicobacter Pylori - H. pylori infection correlates with DNA damage in gastric mucosa cells
Hematology - Findings describe new data in hematology research
Hematology - Major functional genes become deregulated in acute myeloid leukemia subtypes
Hematology - Platelet count can predict development of heparin-dependent antibodies
High-Intensity Focused Ultrasound - Erythrocytes and microbubble contrast agents improve thermal HIFU effects
Hodgkin Disease - Prognostic model for outcome of stem-cell transplantation developed
Human Papillomavirus-Associated Cancer - HPV strongly associated with several cancers independent of HIV infection
Immunology - Study investigated dendritic cell distribution after heart transplantation
Immunotherapy - Pre-emptive immunotherapy prevents relapse in children with MDS after ASCT
Influenza Virus - Avian influenza strain causes lethal systemic infections in ferrets
Ischemia - Administration of ET-1 before ischemia results in a cardioprotective effect
Ischemia - Fibrin-derived peptide B beta(15-42) studied, myocardial protection noted
Ischemia - Study examined contribution of Na+ overload to ischemia-reperfusion injury
Juvenile Myelomonocytic Leukemia - Trend towards graft-versus-leukemia in juvenile myelomonocytic leukemia in ABMT
Legal Issues - Dialysis products company announces receipt of subpoena
Leukemia - AS132 targeted specific proteins for destruction by the proteasome in leukemia
Leukemia - Distinct gene expression patterns linked to FLT3- and NRAS-activating mutations
Leukemia - Eight twenty-one homologues expressed during hematopoietic differentiation
Leukemia - New aspects of chronic lymphocytic leukemia reviewed
Leukemia - Pomolic acid triggered mitochondria-dependent apoptotic cell death in leukemia
Leukemia - SUMO-1 binding required for modification and colocalization with leukemia
Leukemia - SUMO-1 promoted association of SNURF (RNF4) with PML nuclear bodies
Listeria Monocytogenes - Black seed oil inhibits Listeria monocytogenes
Lung Cancer - Glucocorticoids induce 15-PGDH in lung adenocarcinoma cells
Lung Injury Biomarker - Elevated sTNF receptors associated with morbidity/mortality in acute lung injury
Lupus Vulgaris - Misdiagnosis can result in severe skin lesions in lupus vulgaris
Major Depressive Disorder - Hypoalbuminemia may be useful in diagnosis
Mergers & Acquisitions - Biotechnology company acquires Cengent Therapeutics, Inc.
Methadone-Related Rash Outbreaks - Syndromic rash outbreaks affected methadone clinic patients in New South Wales
Myeloma - New, improved staging system effective for multiple myeloma
Nerve Regeneration - Nerve guidance system developed for nerve regeneration/functional recovery
Neuroscience - Biodegradable genipin-cross-linked gelatin conduit material evaluated
Obstetrics - Pregnancy complications related to low levels of anti-clotting proteins
Osteocarcoma - PAF receptor antagonist potent/cytotoxic Ca2+ mobilizer in osteosarcoma cells
Pediatric Leukemia - Spatial analysis of childhood leukemia performed in a case/control study
Peritoneal Dialysis - Rapamycin guides the epithelial-to-mesenchymal transition of peritoneal cells
Personnel - Heart surgeon appointed chair of cardiothoracic surgery at Montefiore Medical
Personnel - James Stewart named chief financial officer by stem cell-focused biotech company
Personnel - Network of nonprofit blood centers names president
Personnel - Neuroscientist and senior NIH administrator fills key scientific post
Pharmaceutical Research - SonoLysis shows promise as a declotting agent for dialysis patients
Product Licensing - Genomics company obtains exclusive license to develop new anemia drug
Pulmonary Medicine - Researchers identify new clinical syndrome caused by hemolysis
Regulatory Issues - Report proposes structure for national network of cord blood stem cell banks
Renal Transplantation - Urinary beta 2-microglobulin studied, cleavage identified
SARS Coronavirus - Reports describe recent advances in SARS coronavirus research
Sclerosing Encapsulating Peritonitis - Clinical features of dialysis-related SEP characterized
Septicemia - Postmortem markers of sepsis studied, serial monitoring reported
Sickle Cell Disease - Long-term outcome determined for children with elevated velocities on TCD
Simian T-Cell Lymphotropic Virus Type 1 - Africa is origin of Tulane primate center STLV-1 sooty mangabey strain
Skin Cancer - 1,25-Dihydroxyvitamin D-3 and analogues protect against UVB-induced DNA damage
Stem Cell Research - A new embryonic stem cell line encodes a key cystic fibrosis mutation
Stem Cell Research - Bone marrow-derived stem cells contribute little to human tumor vessel growth
Stem Cell Research - Hes1 has inhibitory role in Paneth cell differentiation in small intestine
Stem Cell Research - LIF induces kidney stem-like cell multilineage differentiation via cadherin 16
Stem Cell Research - Prolonged-survival neonatal PMNs have enhanced inflammatory/cytotoxic response
Stem Cell Research - Research needed to determine efficient delivery of SCs to appropriate sites
Stem Cell Research - SVP modifies self-renewal SC program to allow chronological change of cell fates
Stem Cell Research - Sonic hedgehog controls stem cell behavior in postnatal and adult brain
Stem Cell Research - VEGF helps embryonic stem cells survive hypoxic stress
Stem Cell Research - alpha1LG4-5 provides vital signals for SC conversion to polarized epithelium
Stem Cell Research - c-Myb and p300 regulate stem cell proliferation and hematopoiesis
Stem Cell Transplantation - Back-up donor identification saves time in unrelated stem cell transplantation
Stem Cell Transplantation - PBSC graft composition affects outcomes after nonmyeloablative conditioning
Stem Cell Transplantation - Relaxation breathing does not improve leukocyte numbers in AHSCT
Stem-Cell Transplantation - Recent findings illuminate research in stem-cell transplantation
Stem-Cell Transplantation - Retinoic acid may heighten risk of bone marrow transplant nephropathy
Suicidal Behavior Gene - Serotonin synthesis genes involved in predisposition to suicidal behavior
Thrombosis - Autoimmune hepatitis accompanies antiphospholipid syndrome
Tissue Engineering - Studies advance knowledge in tissue engineering research
Transplant Medicine - Heart and Lung Transplant Society marks 25 years
Transplant Medicine - New technology helps heart and lung patients awaiting transplants
Transplant Medicine - Noninvasive test to determines risk of rejection in heart transplant patients
Transplant Medicine - Studies add new findings to transplant medicine body of knowledge
Transplant Medicine - VEGF expansion elicits poor long-term outcomes in renal graft recipients
Tuberculosis - Two sputum specimens adequate for pulmonary tuberculosis diagnosis
Umbilical Cord Blood - CB chromosomal aberrations associated with prenatal exposure to carcinogenic PAH
Vascular Graft - Procedure developed to extract RNA from cells seeded onto cylindrical conduits
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