Cancer Inhibitor
Leukemia inhibitory factor receptor characterized in goldfish
Published in Blood Weekly, May 5th, 2005
According to recent research from Canada, "The cytokine leukemia inhibitory factor (LIF) and its receptor LIFR have been extensively characterized in mammals.
"LIF has been shown to mediate the proliferation, differentiation and activation of a number of cell types in various tissues. This paper reports on the identification of a novel LIFR isolated from goldfish (Carassius auratus) macrophages."
"Goldfish LIFR shares a 26% amino acid sequence identity with mammalian LIFR sequences; however it retains all of the conserved amino acid motifs that identify a...
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Source: Blood Weekly (2005-05-05)
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