Susan Hasty, Publisher
Table of Contents . . . May 12th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Artificial Blood Substitute - Liposome-encapsulated actin-Hb used to develop artificial blood substitutes
Blood Safety - Sterile filtration method removes poxvirus from plasma derivatives
Stem Cell Differentiation - Complex extracellular matrices promote tissue-specific stem cell differentiation
Tissue Engineering - Altering scaffolding materials yields optimal MSC-induced bone formation
Transfusion Medicine - Prestorage leucodepletion reduces transfusion reactions events
Acute Mixed Lineage Leukemia - Higher IAP expression associated with chemotherapy-resistant nature of AMLL
Acute Myeloid Leukemia - Arsenic trioxide represses activation of NF-kappa B/COX-2 in AML cells
Acute Myeloid Leukemia - New findings in the area of acute myeloid leukemia described
Angiology - Neurotrophins recruit and mobilize cells to enhance vessel formation
Angiology - Researchers provide details of new studies and findings in the area of angiology
Angiology - Researchers report details of new studies and findings in the area of angiology
Anticancer Therapy - Jasmonates act directly and selectively on cancer cell mitochondria
Apoptosis - Bax and Bak genes required for apoptosis induction by sulforaphane
Apoptosis - CD44 has a modulating role in death receptor-mediated apoptosis
Apoptosis - Cyclooxygenase-2 inhibits ginseng metabolite-mediated apoptosis
Avian Influenza - Avian flu outbreak control integrated human & veterinary health response efforts
Bacteriology - Yersinia species survive and multiply in macrophage phagosomes
SARS - Researchers' work adds to SARS body of knowledge
Biomaterials - Clotting time shortened for HUVECs cocultured with biomaterial-treated monocytes
Biomedical Engineering - Gelatin conduit can be an effective aid for regenerating nerves
Bioterrorism - Multiplexed PCR assay simultaneously detects four biothreat agents
Blood Safety - Committee recommends PolyHeme phase III study continue
Blood Safety - People's Republic of China signs pact with blood safety organization
Brain Cancer - Cyclopamine inhibits tumor growth in brain
Brain Cancer - Mobile phone use not associated with risk of parietal/temporal lobe brain tumors
Breast Cancer - BCAS2 potentiates estrogen receptor transcriptional activity
Breast Cancer - BRCA1/2 germline mutations evaluated in breast cancer moderate/low-risk persons
Business Update - Cell-therapy company strengthens ties with Wisconsin Alumni Research
Business Update - HIV/AIDS report features Hemopurifier developer
Cardiology - Independent studies substantiate biocompatibility of stent coating technology
Cardioprotection - Preischemic administration of trimetazidine protects against I/R injury
Cardioprotection - Pyrroloquinoline quinone is a highly effective cardioprotective agent
Chondrogenesis - PGC-1 alpha regulates chondrogenesis via Sox9 gene association
Clostridium Difficile - slpA gene sequenced from C. difficile strains causing outbreaks in Japan
Collaborations - Companies collaborate on Virtual-Loop technology for type 1 diabetes
Colon Cancer - Short-term risk for colonic polyps in I1307K APC mutation is low
DNA Research - New advances made in DNA damage response network of Fanconi's anemia proteins
Diagnostics - PCR detects pathogenic leptospires earlier than in tissue culture
Diagnostics - Specific dinucleotide repeats identify hemophilia A carriers
Diagnostics - Toxigenic culture sensitive for diagnosis of C. difficile-assoc. diarrhea
Disseminated Tuberculosis - Disseminated TB presented as multiple hepatosplenic microabscesses/pancytopenia
Drug Delivery - PCL-based honeycomb scaffolds developed as drug delivery systems for rhBMP-2
Drug Development - Developed pyrrole derivatives have antimycobacterial activity
Drug Development - Oligosaccharides weak inhibitors of mycobacterial arabinosyltransferases
Enteric Infections - Rifaximin active against enteric infections
Epidemiology - Multiple C. difficile strains in fecal samples limits epidemiology studies
Genetics & Genomics - Commensal Escherichia coli strain harbors many 'virulence-associated' genes
Genetics & Genomics - Molecular elucidation of CML pathogenesis facilitates diagnosis and treatment
Genetics & Genomics - O-specific LPS gene cluster identified in CF-associated B. cenocepacia
Germ Cell Cancer - PARP-1 gene alterations found in germ cell tumors
Graft-Versus-Host Disease - APC requirements are different between CD8 and CD4-mediated acute GVHD
HIV/AIDS Drug Development - HIV receptor site interactions with metallocyclams investigated
HIV/AIDS Drug Development - High-throughput modified ELISA screens HIV-1 pg41 fusion inhibitors
HIV/AIDS Drug Development - NNRTI derivatives more potent against HIV-1 than efavirenz
HIV/AIDS Drug Development - Sulfonated naphthyl porphyrins active against HIV-1
HIV/AIDS Drug Development - Trimeric membrane-anchored gp41 inhibits HIV membrane fusion
HIV/AIDS Mental Health - Apathy correlates with cognitive function but not CD4 status in HIV infection
HIV/AIDS Pathogenesis - B30.2(SPRY) domain is the major determinant of anti-HIV-1 potency
HIV/AIDS Pathogenesis - HIV-1 Nef reduces rate of recycling of transferrin receptor to plasma membrane
HIV/AIDS Pathogenesis - HIV-1 Tat stimulates TC assembly through TBP recruitment in absence of TAFs
HIV/AIDS Pathogenesis - HIV-1 Vpr binds to 14-3-3 proteins and facilitates complex formation with Cdc25C
HIV/AIDS Pathogenesis - HIV-1 causes cell death via HIV-1 Vpr derived C terminal peptide
HIV/AIDS Pathogenesis - Interleukin-7 increases HIV-1 LAI-mediated Fas-induced T-cell death
HIV/AIDS Pathogenesis - Preferential apoptosis of HIV-1-specific CD4+ cells in HIV-infected persons
HIV/AIDS Pathogenesis - SATBI interacts with Tat in HIV-1-infected T cells
HIV/AIDS Research - Research in HIV/AIDS provides new insights
HIV/AIDS Vaccine - Anti-HIV Abs induced to control viremia via complement-mediated inactivation
Hair Studies - Eumelanin hair pigment preserved in proopiomelanocortin-deficient mice
Hematology - Postmortem molecular testing for hereditary thrombophilias may aid relatives
Hematology - Researchers' findings advance hematology research
Hematology - Serum markers herald thrombosis risk in patients with relapsed myeloma
Hematopoiesis - Cell signaling influences SC and its niche in rapidly self-renewing epithelia
Hematopoiesis - Growth factor independence 1 is an intrinsic regulator of stem cell self-renewal
Hematopoiesis - New findings in the area of hematopoiesis detailed
Hematopoiesis - Skeletal muscle is a reservoir for hematopoietic stem cells
Hemodialysis - Tacrolimus 0.1% ointment not effective for dialysis-related pruritis
Hemophilia - Gene therapy completely corrects hemophilia in laboratory animals
Hormone Replacement Therapy - HRT shouldn't be recommended solely to prevent cardiovascular disease
Information Technology - Mobile messaging technology company announces channel partner
Ischemia - Proteins in highly soluble fraction may contribute to cardioprotection
Kaposi Sarcoma-Associated Herpesvirus - KSHV LANA protects lymphoid cells from p16 INK4A-induced cell cycle arrest
Kidney Transplantation - Adenosine increase may be relevant for anti-ischemia and tissue protection
Leukemia - Cognitive changes in children treated for acute lymphoblastic leukemia
Leukemia - Gene expression pattern predicts multiple drug resistance, treatment failure
Leukemia - Leukemia-associated fusion proteins showed multiple paths of cell transformation
Leukemia - Methylation of histones in leukemia used as marker of granulocyte abnormalities
Listeria Diagnostics - Standardization needed for L. monocytogenes detection
Liver Cancer - Additional doxorubicin therapy doesn't improve outcome after liver transplant
Liver Regeneration - Embryonic STO cell-derived xenografts express hepatocytic functions.
Lymphoma - Histone deacetylase inhibitors induce apoptosis in t(14;18) lymphomas
Malaria - TOMOCOMD-CARDD approach identifies antimalarial compounds
Malaria Epidemic - Link between climate variability and malaria epidemics still unproven
Multiple Myeloma - Foundation advances research in myeloma with creation of tissue bank
Mycobacterium Tuberculosis - MTB & M. smegmatis mutants increased beta-lactam antibiotic susceptibility
Mycobacterium Tuberculosis - MTB evades host antimicrobial defenses by inhibiting phagosome maturation
Mycobacterium Tuberculosis - Molecular techniques differentiate MTB strains by genetic polymorphisms
Mycobacterium Tuberculosis - Pathway critical for MTB virulence conserved & functional in M. smegmatis
Mycobacterium Tuberculosis - Peptidoglycan hydrolase Cw1M identified in Mycobacterium tuberculosis
Myelodysplastic Syndromes - REVLIMID new drug application submitted to U.S. FDA for review
Myocardial Infarction - Sodium nitrite gets new medical uses for heart attack and organ damage
Neuritogenesis - Neuritogenesis modulated by topography and nerve growth factor
Neurogenesis - Beta-catenin mediated Wnt signal required to maintain pallium molecular identity
Nosocomial Infections - L. pneumophila persist in water supply regardless of disinfection procedures
Nosocomial Infections - Nosocomial outbreak-related respiratory pathogens reviewed
Oncology - Researchers describe findings in oncology studies
Oral and Maxillofacial Surgery - Platelet-rich plasma doesn't improve outcome of cranial bone grafts
Proteome - Global effects of BCR/ABL and TEL/PDGFR beta expression on the proteome detailed
Proteomics - Rv3676 protein naturally defective in Mycobacterium bovis BCG strains
Proteomics - The serine/threonine kinase pim-1 has multifunctional properties
Psittacosis Outbreaks - Psittacosis outbreak may be linked to wild birds
Pulmonary Medicine - Combined cell and gene therapy remedies pulmonary hypertension
Renal Transplantation - Gene expression of proinflammatories is augmented in kidneys from NHB donors
SARS Coronavirus - SARSCoV mutation rates correlate with geographic epidemic characteristics
SARS Coronavirus - Safe & sensitive Spike protein-based IFA detects antibody responses to SARS-CoV
Simian Immunodeficiency Virus - Unliganded/fully glycosylated SIV gp120 structure determined
Staphylococcus Aureus - S. aureus nasal carriage not assoc. with Vitamin D receptor gene mutation
Stem Cell Research - Cell line developed to study germ line stem cell biology
Stem Cell Research - Early fetal liver readily repopulates B lymphopoiesis in adult bone marrow
Stem Cell Research - Embryonic stem cell neural induction generates dopamine neurons
Stem Cell Research - G-CSF-induced uPAR upregulation associated with increased uPAR shedding
Stem Cell Research - Galectin-1 increases granulocyte-macrophage/erythroid colonies
Stem Cell Research - Menin suppresses osteoblast differentiation by antagonizing AP-1 factor JunD
Stem Cell Research - Neuroblast marking provides a tool for exploring neural stem cell genetics
Stem Cell Research - Neuropoiesis results in abnormal nestin/GFAP expression in intracranial glioma
Stem Cell Research - Neurulation protein CECR2 forms a chromatin remodeling complex with SNF2L
Stem Cell Research - SCF synergistically enhances TPO-induced STAT5 signaling in megakaryocyte SCs
Stem Cell Research - Stat3 negatively regulates G-CSF signaling by inducing SOCS3 expression
Stem Cell Research - Transcriptome profiling identifies divergent paths required to maintain SC state
Stroke - eNOS stimulates reparative growth factors following cerebral ischemia
Tissue Engineering - Anionic hydrogels improve cell adhesion and proliferation
Tissue Engineering - Chondrocyte endochondral ossification influenced by polyester crystallinity
Tissue Engineering - MSC osteogenesis influenced by sponge composition of gelatin/betaTCP scaffolds
Tissue Engineering - Method developed to pattern proteins & cells on PLA/PLGA for tissue engineering
Tobacco Use - Diet and tobacco exposure to acrylamide influence hemoglobin AA-adduct levels
Transplant Medicine - ABCB1 haplotypes influence tacrolimus levels in lung transplant patients
Transplant Medicine - Data advance knowledge in transplant medicine research
Transplant Medicine - Data: CyIS improves long-term survival in lung-transplant patients
Transplant Medicine - Pediatric immune systems study to improve young transplant patients' treatments
Tuberculosis - Isoniazid binds to NAT enzyme in mycobacterial cells
Tuberculosis Diagnosis - Culture more sensitive than PCR for extrapulmonary tuberculosis diagnosis
Tuberculosis Drug Development - Quinchamalium majus constituents have potential antitubercular activity
Tuberculosis Vaccine - Prescreening program tested a wide range of tuberculosis vaccines
Tumor Invasion - Mammary ducts showed a different frequency of white blood cell infiltration
Tumor Suppression - Rb tumor suppressor in stress responses and hematopoietic homeostasis analyzed
Urogenital Cancer - Immunogenetic basis for high urogenital cancer prevalence in sea lions
West Nile Virus - Studies describe new findings in west nile virus research
Yersinia - Invasin triggers Rac1-mediated signals enabling Yersinia internalization
Yersinia - LAT/SLP-76 molecules targeted by Yersinia to inhibit T cell activation
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