Neuroblast marking provides a tool for exploring neural stem cell genetics

"The studies of neural stem cell fate, as well as the possibility to genetically manipulate them, represent important tools for modem neuroscience research. Furthermore, the potential use of these cells in treatment of neurological disorders makes these methods valuable for the development of new treatment paradigms. Here we report a method to genetically mark and modify neuroblasts and progenitor cells in the subventricular zone of postnatal rats using retroviral vectors," scientists writing in the Journal of Neuroscience Methods report.

"Using GFP as a marker gene we...

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