Stem Cell Research
Boost HSC decreases donor chimerism/graft dysfunction in PID patients
Published in Blood Weekly, May 26th, 2005
"Hemopoietic stem cell transplants (HSCT) cure increasing numbers of primary immunodeficiencies (PID): residual recipient T-cell function increases risk of incomplete or decreasing immune reconstitution, which may resolve following a second, unconditioned, infusion from the same donor (boost infusion).
"We assessed the outcome of 20 boost infusions in 19/139 patients transplanted for PID patients at our center since 1987. Boost infusion was given 64-1226 days after the original HSCT. Follow-up was 4-124 months,"...
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Source: Blood Weekly (2005-05-26)
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