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Tissue Engineering

Hydrophobicity is design criterion for bone tissue engineering polymer scaffolds

Published in Blood Weekly, May 26th, 2005

Hydrophobicity is used as a design criterion for bone tissue engineering polymer scaffolds.

According to a study from the Netherlands, "Porous polymeric scaffolds play a key role in most tissue-engineering strategies. A series of nondegrading porous scaffolds was prepared, based on bulk-copolymerisation of 1-vinyl-2-pyrrolidinone (NVP) and n-butyl methacrylate (BMA), followed by a particulate-leaching step to generate porosity."

"Biocompatibility of these scaffolds was evaluated in vitro and in vivo. Furthermore, the scaffold materials were studied using the so-called demineralized bone matrix (DBM) as an evaluation system in vivo.

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