Published in Blood Weekly, May 26th, 2005
"The HOX family of homeobox genes plays an important role in normal and malignant hematopoiesis. Dysregulated HOX gene expression profoundly effects the proliferation and differentiation of hematopoietic stem cells (HSCs) and committed progenitors, and aberrant activation of HOX genes is a common event in human myelold leukemia. HOXB6 is frequently overexpressed in human acute myeloid leukemia (AML)," researchers in the United States report.
"To gain further insight into the...
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