Published in Blood Weekly, May 26th, 2005
"Membrane-associated Leishmania Ags (MLA) or soluble Leishmania Ags were used in vitro to stimulate cord blood or PBMC from healthy donors noninfected by Leishmania parasites.
"MLA, but not soluble Leishmania Ags, constantly induce strong proliferation of cord blood mononuclear cells-and PBMC from noninfected individuals. Responding cells are CD3+, CD4+, TCRalphabeta+, CD45RO+, and CD45RA+ and secrete IFN-gamma and IL-10, but not IL-4," investigators in Tunisia report.
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