Mycobacterium Smegmatis
FadD32 and accD4 genes essential for survival of Mycobacterium smegmatis
Published in Blood Weekly, May 26th, 2005
According to a study from France, "Mycolic acids are major and specific long-chain fatty acids of the cell envelope of several important human pathogens such as Mycobacterium tuberculosis, M. leprae, and Corynebacterium diphtheriae. Their biosynthesis is essential for mycobacterial growth and represents an attractive target for developing new antituberculous drugs."
"We have previously shown that the pks13 gene encodes condensase, the enzyme that performs the final condensation step of mycolic acid biosynthesis and is flanked by two...
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Source: Blood Weekly (2005-05-26)
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