Blood Weekly

Diagnostics - High-throughput analysis detects genomic DNA in blood at a rapid pace

Embryonic Stem Cell Research - More embryos reach blastocyte stage in vitro without leukemia inhibitory factor

Neural Stem Cell Research - Intraspinal NSC graft improves motor recovery/causes aberrant axonal sprouting

Stem Cell Transplantation - p53 gene deletion adverse prognostic factor in multiple myeloma after ASCT

Tissue Engineering - T2 mapping permits evaluation of cartilage repair after biomaterial implantation

Acute Lymphoblastic Leukemia - Company initiates phase I/II clinical trial of talotrexin in patients with ALL

Acute Myelogenous Leukemia - U.S. FDA grants orphan drug designation for Troxatyl

Acute Myeloid Leukemia - Dominant negative effects of AML1/ETO may be important for AML pathogenesis

Alzheimer Disease - Presenilins affect caveolin 1 trafficking in an indirect manner

Anthrax -  B. anthracis spores contaminate soil surrounding infected bison carcasses

Antimycobacterial - Kahalalide A and related analogues have antimycobacterial activity

Leukemia - Studies describe new findings in leukemia research

Apoptosis - Boswellic acid acetate induces apoptosis via caspase-mediated pathways

Avian Influenza - Molecular properties from highly pathogenic avian influenza virus characterized

Blood Products - Company developing synthetic blood substitute selects contract researcher

Blood Safety - Publication of new human erythrocyte antigen BeadChip Test study announced

Bone Marrow Collection - BM CD34+ cell count predicts adequate peripheral progenitor cell collection

Bone Regeneration - Bone marrow and periost destruction impairs bone healing

Stem Cell Transplantation - Reports advance knowledge in stem cell transplantation research

Breast Cancer - NCOA3 polymorphisms associated with protective effect against breast cancer

Breast Cancer - Test predicts risk of blood clots in women receiving tamoxifen therapy

Business Update - Stem cell-focused biotechnology company reports shareholder resolutions

Candida Albicans - Source of Candida albicans hospital outbreak is mostly endogenous

Cardiology - Reports describe recent advances in cardiology research

Cardiopulmonary Bypass - Nitric oxide gas and iloprost reduces platelet dysfunction during CPB

Cardiovascular Disease - Telemedicine systems company and St. Jude Medical expand alliance

Cardiovascular Disease Prevention - Hormone replacement therapy reduces left ventricular mass

Catheter-Related Bloodstream Infection - Three techniques for in situ diagnosis compared

Cervical Cancer - HLA-B8 overrepresented in cervical cancer compared to MHC-1 in healthy controls

Chemotherapy - Early responses to chemotherapy of hematologic cells prognosticated child ALL

Cholera - Adult nonbiting midges possible windborne carriers of V. cholerae nonO1/O139

Chondrogenesis - Smad3 induces chondrogenesis through SOX9 activation via CBP/p300 recruitment

Coronary Artery Bypass Grafting - Perioperative RBC transfusion linked to increased mortality risk

DNA - DNA repair gene TP53/POLI/REV1/LIG4 SNPs associated with lung cancer risk

Deep Vein Thrombosis - Company provides update on FIBRIMAGE development program

Dengue Fever - Dual infection with dengue 2 and 3 viruses documented after trip to Sri Lanka

Diagnostics - Company to begin trials of blood test for cervical, other HPV-associated cancers

Diagnostics - Delaware hospital acquires semi-automated blood volume analyzer

Diagnostics - Veterans services network awards blood gas standardization 5-year contract

Drug Development - Company applies to FDA for orphan drug status of lysosomal acid lipase product

Drug Development - U.S. FDA grants approval of formulation for cardiovascular product fenofibrate

Embolism - Clinical outcome of patients with venous thromboembolism transcribed

Embryogenesis - Fibronectin upregulated during differentiation to extraembryonic endoderm fate

Embryonic Stem Cell Research - Directed differentiation of telencephalic precursors from ESCs demonstrated

Embryonic Stem Cell Research - Early human embryos should not be recipients of direct moral consideration

Embryonic Stem Cell Research - bFGF and BMP signaling suppression sustain undifferentiated ESC proliferation

Environmental Carcinogen - Newborn carcinogen-DNA adduct levels similar to or higher than exposed mothers

Epstein-Barr Virus - EBV BARF1-encoded protein expressed from tetracycline-regulatable ADV system

Exercise and Health - H-1 receptor-mediated vasodilatation contributes to postexercise hypotension

Extended-Spectrum Beta-Lactamase Enterobacter -  Enterobacter ESBL presence due to plasmid-mediated gene transfer

Finance - Cell therapeutics-focused corporation announces third quarter 2005 results

Finance - Company raises $16M to advance stem cell-based therapies

Finance - Hemodialysis products manufacturer reports financial results

Finance - Medical school gets $4 million to make "smart nanoparticles"

Finance - Stem cell-focused biotechnology company reports first quarter 2005 results

Gastroenterology - Jaundice affected wound recovery in patients with pancreatobiliary obstruction

Gene Expression - LKLF-regulated genes identified in quiescent CD4+ T lymphocytes

HIV/AIDS & Malaria Coinfection - Blood-stage malaria increase not generally observed in HIV infection

HIV/AIDS Drug Development - 'Ureidopeptide' substrate analog inhibits HIV-1 protease

HIV/AIDS Drug Development - HIV-inactivating protein isolated from red alga Griffithsia sp

HIV/AIDS HAART - HAART alters adipokine expression and insulin sensitivity of adipose tissue

HIV/AIDS Life Expectancy - Negative association between adult HIV prevalence and life expectancy

HIV/AIDS Neural Pathogenesis - Ethanol potentiates HIV-1 gp120-induced neuronal injury

HIV/AIDS Neural Pathogenesis - HIV-1 Tat promotes survival of astrocytic host

HIV/AIDS Pathogenesis - Critical domain definition required for homophilic sidekick molecule targeting

HIV/AIDS Pathogenesis - HIV-1 Tat-coactivator interactions may contribute to neuronal apoptosis

HIV/AIDS Pathogenesis - HIV-1 capsid cysteine residues regulate oligomerization and CypA-induced changes

HIV/AIDS Quality of Life - Appropriate drug management helps HIV/AIDS patients improve quality of life

HIV/AIDS Risk Factors - Taxi drivers in a Masaka slum at high risk of HIV/STD due to lack of education

HIV/AIDS Vaccine - Clade B vaccine elicits response against conserved epitopes in multiple clades

HIV/AIDS Vaccine Development - Synthetic vaccine antigen construct detects HIV-induced humoral responses

HIV/AIDS Vaccine Research - HIV preventative vaccine program developed a strategy based on lipopeptides

HIV/AIDS-Related Cryptococcosis - Cryptococcosis incidence decreased in HIV-positive patients prior to HAART era

Hematology - Bcl-2 antisense G3139 uptake is achievable in acute myeloid leukemia cells

Hemochromatosis - Research casts new light on genetic iron overload

Hemodialysis - Novel flow monitoring device may provide early warning of access graft failure

Hemophilia Therapy - Guidelines for recombinant activated factor VII use released

Immunology - V gamma 9N delta 2 effector T cells express killer cell lectin-like receptor G1

Ischemia - Ischemic preconditioning examined, effect on behavioral deficits clarified

Ischemia - Studies advance knowledge in ischemia research

Klebsiella Pneumoniae Outbreaks - Biotyping/ribotyping/PFGE distinguished ESBL-K. pneumoniae outbreak strains

Leucodepletion - Alloimmunization to red blood cells after leucodepletion examined

Leukemia - BCR-ABL induced expression of Skp2 and proliferation of CML cells