Stem Cell Gene Therapy
Breast cancer resistance protein is marker in SC gene therapy applications
Published in Blood Weekly, June 9th, 2005
"Breast cancer resistance protein (BCRP) was identified 7 years ago as the most recent member of ABC drug efflux membrane transporters. It is a 655 amino acid peptide with an ability to extrude a wide variety of chemical compounds from the cells.
"Today, it is considered as one of three major transporters causing drug resistance in mammalian cells. It is also distributed in epithelia involved in drug disposition with major role in the placenta, liver and intestine," scientists in Czech Republic wrote.
"In addition," said F. Staud and colleagues,...
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Source: Blood Weekly (2005-06-09)
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