Stem Cell Research

Activated CB DCs kill tumor cells without damaging normal hematological SCs

Published in Blood Weekly, June 16th, 2005

Activated umbilical cord blood dendritic cells kill tumor cells without damaging normal hematological stem cells.

According to recently published research from Japan, "Apart from their role as antigen presenting cells, human peripheral blood monocyte and CD34+ cell-derived dendritic cells (DC), have been demonstrated to exert cytotoxicity against some tumor cells, and their tumoricidal activity can be enhanced by some stimili.

"However, there have been no reports concerning the tumoricidal activity of human cord blood dendritic cells (CBDC). In this article, we report that human cord blood monocyte-derived DC acquire the ability to kill hematological...

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Source: Blood Weekly (2005-06-16)

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