Blood Weekly
Susan Hasty, Publisher
Table of Contents . . . June 30th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Blood Weekly | Other Publications
Angiology - Transillumination tomography used for imaging of tissue-engineered blood vessels
Bioartificial Liver - Directed differentiation of bone marrow cells yields hepatocyte-like cells
Blood Group Typing - Microarray assay used to type DNA and detect new alleles in donor cohorts
Red Blood Cell Substitute - Red blood cell substitute has no significant side effects
Transfusion Medicine - Pooling of whole blood platelets does not lower efficacy
Adenovirus Outbreak - Neonatal ICU adenovirus type 30 outbreak spread via ophthalmologic procedures
Age-Related Macular Degeneration - Phase I/II data reported for Lucentis in combination with Visudyne trial
Alzheimer Disease - Pharma company acquires rights to implant stem cells for Alzheimer disease
Anemia - CD4+ CD25+ regulatory T cells control induction of AIHA
Anemia - Common Fanconi's anemia mutation found in black population of sub-Saharan Africa
Angiology - New data illuminates research in angiology
Antimicrobial - Hoechst 33258 active against P. carinii/C. albicans/C. dubliniensis
Antioxidative System - Imbalance of antioxidative system in satellite cells is age-dependent
Arteritis - Autoantibody repertoires in small- and medium-sized vessel vasculitides analyzed
Atherosclerosis - Atherosclerotic lesions analyzed, influence of deficient bone marrow revealed
Atrial Fibrillation - Article reviews current therapeutic options for atrial fibrillation
Blood Safety - CE Mark granted Leukotrap Affinity Prion Reduction Filter System
Breast Cancer - Researchers detail new studies and findings in the area of breast cancer
Burkholderia Cepacia Outbreak - B. cepacia outbreak caused by Albuterol nebulization solution contamination
Business & Finance - Danish producer of patch clamping devices reports on sales, marketing, growth
Business Update - Agreement signed to sell fibrin sealant for orthopedic surgery in Netherlands
Cardiology - Pre-market notification submitted to U.S. FDA to expand technology labeling
Catheter Occlusions - Catheter occlusions studied
Chronic Kidney Disease - Caution required when using enoxaparin in patients with chronic kidney disease
Coagulation - Factor VIIa studied, dimerization-mediated activity enhancement shown
Collaborations - American Red Cross lets manufacturing agreement for immunoglobulin expire
Crimean-Congo Hemorrhagic Fever Outbreak - Simple barrier methods may prevent Crimean-Congo hemorrhagic transmission
DNA Research - Treponemal DNA not preserved in bone
Dengue Fever - T helper 1 reaction altered in patients with dengue hemorrhagic fever
Dengue Virus Epidemic - Virus evolution pattern detected during a severe dengue epidemic in Cuba
Diagnostics - FDA clearance received for PreAnalytiX PAXgene Blood RNA System
Diagnostics - Method for monitoring chronic myeloid leukemia developed
Drug Development - U.S. NIH awards $3,700,000 drug development grant for epilepsy prodrug research
ESBL-Producing Escherichia Coli - MSLT more discriminatory than PFGE in identifying ESBL-producing E. coli
Embolism - Cardiovascular events occurring after acute pulmonary embolism analyzed
Embryonic Development - E-cadherin intron 2 has cis-regulatory elements essential for gene expression
Embryonic Stem Cell Research - Delta CD4 expression in differentiated ESCs may enable rapid cell purification
Embryonic Stem Cell Research - Developmental pluripotency associated 5 may have important role in ESC stemness
Embryonic Stem Cell Research - Embryonic stem cell lines derived using serum-free medium
Embryonic Stem Cell Research - Embryonic stem cells maintain genomic stability during in vitro propagation
Embryonic Stem Cell Research - JAK2/STAT3 directs cardiomyogenesis within embryonic stem cells
Embryonic Stem Cell Research - Telomerase improves proliferation of embryonic stem cells
Environmental Health - Is there a link between childhood cancer and overhead power lines?
Environmental Pathogen - More bacterial pathogens identified in therapy pools compared with potable water
Escherichia Coli O157:H7 Outbreak - Escherichia coli O157:H7 outbreak associated with ground beef contamination
Fetal Hypoxia - Delta4 helps regulate hematopoiesis after hypoxic stress in the fetus
Generic Drugs - U.S. FDA grants approval of generic antibiotic Biaxin Tablets 250 mg and 500 mg
Graft-Versus-Host Disease - High doses of transplanted CD34+ cells linked to lower risk of graft rejection
HIV & Human Papillomavirus Pathogenesis - HPV and HIV infections may influence cervical cytokine intralesional levels
HIV/AIDS Diagnostics - Duplex real-time PCR assay detects HIV DNA in dried blood spots
HIV/AIDS Drug Development - HIV fusion inhibitor enfuvirtide has a favorable safety and tolerability profile
HIV/AIDS Drug Development - Pertussis toxin B-oligomer inhibits HIV infection and replication
HIV/AIDS Emotional Support - Older adults with HIV/few comorbid illnesses report inadequate emotional support
HIV/AIDS Epidemiology - "Surplus" men in China may become significant new HIV risk group
HIV/AIDS Healthcare - Evolving health delivery system designed to meet needs of changing HIV epidemic
HIV/AIDS Infection - Apoptosis may prevent HIV-1 infection in an exposed but uninfected population
HIV/AIDS Infection - Lewis b antigen has a slight protective effect on HIV infection
HIV/AIDS Pathogenesis - Findings describe new data in HIV/AIDS pathogenesis research
HIV/AIDS Pathogenesis - HIV K65R mutations associated with TAM can be borne by the same virus
HIV/AIDS Pathogenesis - HIV-1 envelope V2 region influence HIV entry and spread in macrophages
HIV/AIDS Pathogenesis - HIV-1 gp41 loop segment peptide binds and interacts with phospholipid membranes
HIV/AIDS Pathogenesis - MSD-replacement mutants severely impair HIV fusion activity
HIV/AIDS Pathogenesis - Mannose receptor is potential intracellular target of HIV-1 Nef
HIV/AIDS Pathogenesis - Tissue macrophages are productively infected by primary X4 HIV-1 isolates
HIV/AIDS Prevention - HIV-infected mothers more likely to discuss risk factors with their children
HIV/AIDS Prevention - Latin America/Caribbean nongovernmental organizations help prevent HIV infection
HIV/AIDS Risk - Recent incarceration independently associated with syringe sharing
HIV/AIDS Vaccine - Majority of HIV-1B fails to prime CTL response against HLA-A2-restricted epitope
HIV/AIDS Vaccines - Findings in HIV/AIDS vaccines provide new insights
Haemophilus Influenzae - H. influenzae most common bacterium isolated from sputum in AECOPD patients
Hematology - Flow system determines dextrose in parenteral, hemodialysis solutions
Hematopoiesis - GM-CSF and accessory cells modulate radioprotection by hematopoietic cells
Hematopoiesis - Reports add new data to hematopoiesis research
Hemophilia - Researchers demonstrate long-term therapeutic gene therapy for HA in dogs
Hepatic Tuberculosis - Hypercalcemia in hepatic tuberculosis resolved with antituberculosis medication
Hepatitis C Virus - Advances made in diagnosing hepatitis C infection in HIV± patients
Hepatitis C Virus - Compartmentalization of HCV genotypes between plasma and PBMC observed
Hepatitis C Virus - Human serum facilitated hepatitis C virus infection
Hodgkin Lymphoma - Interleukin-4 cytotoxin may be a unique agent against Hodgkin lymphoma
Infectious Disease - Rotavirus probable cause of large outbreak in Indonesia
Information Technology - California blood bank extends software information, regulatory system
Interferon - Peginterferon alfa-2b plus ribavirin treatment evaluated in children with HPC
Kaposi Sarcoma-Associated Herpesvirus - 18 major KSHV proteins of viral and cellular origin identified
Kaposi Sarcoma-Associated Herpesvirus - CD21 and CD23 gene expression induced by KSHV transcription activator
Kidney Cancer - Hemorrhagic complications occurred after nephron-sparing surgery
Leucocytes - Mechanisms involving leucocytes, endothelial cells involve interrelationships
Leukemia - Activation of the RAS pathway predicted chemosensitive phenotype of AML blasts
Leukemia - Alteration of p73 associated with acute myelogenous leukemia
Leukemia - Conversational strategies recommended for parents of diagnosed leukemic children
Leukemia - Early versus late insertion times of central venous lines compared
Leukemia - Electrolyte abnormalities of acute lymphocytic leukemia linked to renal damage
Leukemia - Genes linked to treatment resistance in children with leukemia
Leukemia - Genetic classification of adult acute lymphoblastic leukemia performed
Leukemia - Role of transplantation for infants with acute lymphoblastic leukemia defined
Liver Failure - Etiology and prognosticators of pediatric fulminant hepatic failure profiled
Liver Regeneration - Portal application of CD133+ BM stem cells may enhance hepatic regeneration
Lymphoma - Alcohol may lower risk of non-Hodgkin lymphoma
Malaria - Factors influencing the pattern of imported malaria determined
Milk Pasteurization - Pasteurization inactivates M. avium subsp paratuberculosis in milk
Multiple Myeloma - Novel combination overcomes drug-resistant myeloma cells
Mycobacerium Bovis - Mycobacerium bovis persists in farm environment outside of host
Mycobacterium Diagnostics - PCR assay identifies Mycobacterium species in contaminated cultures
Mycobacterium Tuberculosis - Blood agar rapidly tests susceptibility of MTB to isoniazid and rifampin
Mycobacterium Tuberculosis - Cyclic AMP-regulated genes identified in Tuberculosis complex mycobacteria
Mycobacterium Tuberculosis - MTB families identified that are specific to Spain-related settings
Mycobacterium Tuberculosis - Macrolide derivatives active against Mycobacterium tuberculosis
Mycobacterium Tuberculosis - Modified immunohistological staining detects Ziehl-Neelsen-negative MTB
Mycobacterium Tuberculosis - Two low-cost colorimetric methods rapidly detect ofloxacin resistance in MTB
Mycobacterium Tuberculosis Diagnostics - Real-time PCR rapidly detects Mycobacterium tuberculosis in clinical samples
Mycobacterium Tuberculosis Drug Development - Computer-aided ligand design used for structure-based drug design
Myelodysplastic Syndrome - Clinical features of Chinese patients with MDS compared with Western patients
Myelodysplastic Syndrome - Clinical importance of transforming growth factor-beta analyzed in MDS patients
Myelodysplastic Syndrome - Single-nucleotide polymorphism of G-CSF receptor gene heightened risk for MDS
Myeloid Dysplasia - Flow cytometry diagnosed erythroid and myeloid dysplasia
Myeloma - MRI findings correlated with histological results in multiple myelomas
Neisseria Meningitidis - Variable-no. tandem repeats used to examine N. meningitidis gene diversity
Nerve Regeneration - Fibrous biodegradable polymer conduits developed for guided nerve regeneration
Neural Stem Cell Research - Focal cortical ischemia leads oligodendrocytes production/neural repair
Neural Stem Cell Research - High cell-density seeding increases dopamine neuron yield in culture
Neural Stem Cell Research - Hippocampal ischemic damage severity correlates with enhanced SC induction
Neural Stem Cell Research - Schwann cells induce neuronal differentiation of bone marrow stromal cells
Norovirus - One-step RT-PCR rapidly detects noroviruses in fecal and shellfish samples
Obesity - "Thrifty genes" may be partly responsible for obesity
Obstetrics - Recent studies add new data to obstetrics research
Oral Mucositis - Single-dose phase I data on velafermin (CG53135) announced
Parkinson Disease - Cripto used as a target for improving ESC-based therapy in Parkinson disease
Patents - U.S. patent granted for modified pectin drugs to treat angiogenesis diseases
Personnel - Immortalized nontumorigenic human hepatocytes Sr. VP signs new contract
Pharmaceutical Research - Higher doses of clopidogrel yields quicker platelet inhibition, study shows
Professional Education - School for integrated blood conservation opens
Prostate Cancer - Immortal human prostate epithelial cell line established
Salmonella Outbreak - Raw egg shells in meringue pie cause of Salmonella outbreak in cafeteria
Sepsis - PKCalpha depletion underlies monocyte/macrophage desensitization
Septicemia - Heme oxygenase studied, effects of early expression in leukocytes reported
Sickle Cell Disease - Trait offers malaria immunity to children
Simian Immunodeficiency Virus - Anti-inflammatory profiles protect against AIDS in early SIV infection
Simian Immunodeficiency Virus - SIV entry/replication in astrocytes regulated by transmembrane protein
Spermatogenesis - Etoposide is clastogenic to dividing spermatogonia
Spermatogenesis - Maintenance of spermatogenesis requires gonad specific TAF4b
Stem Cell Aging - Locus on chromosome 2 regulates hematopoietic stem cell aging
Stem Cell Research - Activin A maintains embryonic stem cell pluripotency in absence of feeder layers
Stem Cell Research - Bioethicists urge more protection for women donating eggs for stem cell research
Stem Cell Research - CD34+ corneal stromal cells are bone marrow-derived and express HSC markers
Stem Cell Research - FGF-2 enhances the mitotic/chondrogenic potentials of adult BM-derived MSCs
Stem Cell Research - MSCs inhibit lymphocyte proliferation by mitogens and alloantigens differently
Stem Cell Research - Mesenchymal stem cells localize within hematopoietic sites throughout ontogeny
Stem Cell Research - PBMCs acquire myofibroblast characteristics in granulation tissue
Stem Cell Research - Sonic hedgehog and retinoic acid promote sensory fate specification from BMSCs
Stem Cell Research - Stem Cell Therapeutic and Research Act of 2005 passes House of Representatives
Stem Cell Research - Stem cells can undergo spontaneous transformation following long-term culture
Stem Cell Research - Two researchers to join California university's stem cell research efforts
Stem Cell Transplantation - Real-time PCR monitors adenovirus DNA load in stem cell transplant recipients
Stem Cell Transplantation - Recent findings illuminate research in stem cell transplantation
Stroke - Telemedicine, 'stroke box' initiatives get help to acute stroke victims quickly
Surgical Technology - Autologous thrombin processing device receives CE Mark to allow sales in Europe
T-Cell Leukemia/Lymphoma - Allo-HSCT appears to provide sustained long-term survival for ATLL patients
Thalassemia - Humanized mouse model carries common beta(0)-thalassemia mutation
Thalassemia - Structural rearrangements keep alpha-hemoglobin stable
Thrombosis - Complications arose from subcutaneous infusion ports
Thrombosis - Genetic variation alters response to common anticlotting drug
Tissue Engineering - IGF is effective and economical choice for use in TMJ disc tissue engineering
Tissue Engineering - Metabolically active dermal replacement is substitute for autogenous grafts
Transfusion Medicine - Global Med sub and Rex Healthcare ink second deal
Transfusion Medicine - Results identify subclinical HD among T. cruzi seropositive blood donors
Transplant Medicine - ImmuKnow receives clinical support in five independent studies
Transplant Medicine - Most patients given everolimus and low-dose CsA can stop steroids after a week
Transplantation Medicine - Diabetics with renal disease can be re-transplanted with SPK
Tuberculosis - Clinical tuberculosis symptoms necessary to predict high PPD antibody titers
Tuberculosis - High prevalence of pulmonary TB in patients seen at DOTS clinics in Nigeria
Tuberculosis - Incidence of extrapulmonary tuberculosis lower than pulmonary TB in Estonia
Tuberculosis - Matrix metalloproteinase-9 is increased in tuberculous pleural effusions
Tuberculosis - Quality improvement in disease management increases tuberculosis drug compliance
Tuberculosis - Reports describe recent advances in tuberculosis research
Tuberculosis Diagnosis - Blood-based TB test matches up to old skin test in study among health workers
Tuberculosis Diagnostics - Pulmonary tuberculosis rapidly diagnosed via mass spectrometry method
Tuberculous Meningitis - Ligase chain reaction sensitive/specific for tuberculous meningitis diagnosis
Type 2 Diabetes - Acute nateglinide administration may reduce cardiovascular risk in diabetics
Ultraviolet-B Radiation - Karatinocyte UVB response differs according to location in undulating epidermis
Vancomycin-Resistant Enterococci Outbreak - VRE outbreaks in Italy due to spread of a multidrug-resistant VREfm clone
Venous Thromboembolism - U.S. FDA approves new ARIXTRA indication: prevention of VTE in abdominal surgery
Ventilator-Associated Pneumonia - Ventilator-associated pneumonia more prevalent in antibiotic prevention studies
West Nile Virus - Biotech launches vaccine program to protect native Hawaiian birds from West Nile
West Nile Virus - Multifaceted surveillance plan decreases West Nile virus infection risk
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