Acetaminophen

Fever control in septic shock examined, benefit or harm probed

Published in Blood Weekly, July 7th, 2005

Recently published research from Belgium has elucidated fever control in septic shock.

"The beneficial effects of interventions to control fever in sepsis are controversial. We investigated whether the use of acetaminophen and external cooling is beneficial to control fever in septic shock."

"We studied 24 fasted, anesthetized, invasively monitored, mechanically ventilated female sheep (27.0±4.6 kg) that received 0.5 g/kg body weight of feces into the abdominal cavity to induce sepsis," wrote F.H. Su and colleagues, Erasme University Hospital.

"Ringer's lactate (RL) was titrated to maintain pulmonary artery occlusion...

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Source: Blood Weekly (2005-07-07)

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