HIV/AIDS Pathogenesis
Researchers' findings advance HIV/AIDS pathogenesis research
Published in Blood Weekly, July 28th, 2005
Study 1: HIV-1-specific CTL responses in the blood mirror those seen in the mucosal department in natural chronic infection.
According to recent research published in the Journal of Virology, "Gut-associated lymphoid tissue is the major reservoir of lymphocytes and human immunodeficiency virus type I (HIV-1) replication in vivo, yet little is known about HIV-1-specific CD8+ T-lymphocyte (CTL) responses in this compartment.
"Here we assessed the breadth and magnitude of HIV-1-specific CTL in the peripheral blood and sigmoid colon...
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Source: Blood Weekly (2005-07-28)
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