Ischemia

Review focuses on statin-mediated protection against I/R injury and infarction

Published in Blood Weekly, August 11th, 2005

Statin mediated protection of the ischemic myocardium was the focus of a recent report.

"Hypercholesterolemia is a major risk factor in the development of cardiovascular disease and HMG-CoA reductase inhibitors (i.e. statins) were originally designed to reduce serum cholesterol levels and thus reduce this risk factor. However, it has become increasingly apparent that the effects of statins extend well beyond their lipid lowering actions, and these pleiotropic effects have a major role in protecting the myocardium against ischemic injury," scientists in the United States report.

D.G. Wright and D.J. Lefer from Louisiana State University continued,...

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Source: Blood Weekly (2005-08-11)

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