Kidney Transplantation
Early post-transplant blood cyclosporine level predicts rejection
Published in Blood Weekly, August 11th, 2005
"Target organs express antigens directly recognized by antigen-specific T cells, thereby precipitating rejection," scientists in Italy explained. "When early T-cell activation is inhibited, there is a low risk of rejection."
In their study, E. Gotti and coauthors working at the Mario Negri Institute for Pharmacological Research "sought to determine the predictive values of serial posttransplant blood cyclosporine trough (C0 ) concentrations to minimize the risk for a first rejection episode compared with 2-hour postdose (C2 )...
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Source: Blood Weekly (2005-08-11)
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