Blood Weekly

Cryopreservation - Open-freezing system allows survival of cryopreserved ovarian tissue

Hemophilia - Gene therapy induces tolerance to factor VIII inhibitors

Stem Cell Research - HSC mobilization speeds renal function recovery independent of SC contribution

Stem Cell Research - Monocyte-derived Neohepatocytes developed for autologous cell therapy

Stem Cell Transplantation - Transplant of dHGF-cultured hepatocytes prolongs survival of acute liver failure

AIDS-Related Emphysema - AIDS-related emphysema partly due to direct alveolar macrophage HIV-1 infection

Acinetobacter Baumannii Outbreak - Carbapenem-resistant Acinetobacter baumannii cause of hospital outbreak

Age-Related Macular Degeneration - Results from phase III MARINA study reported

Allergy & Immunology - Putative regulatory T cells impaired in CB from hereditary allergy risk neonates

Angiology - Arterial stiffness may play an important role in thrombotic events

Angiology - Enoxaparin prevented thromboembolism associated with central vein catheter

Angiology - Researchers report details of new studies and findings in the area of angiology

Anthrax - Researchers describe findings in anthrax studies

Antiphospholipid Syndrome - Anticoagulation therapy for antiphospholipid syndrome is subject of debate

Apoptosis - Citral demonstrated anticancer activity

Aspergillosis - Pulmonary zygomycosis distinguished from invasive pulmonary aspergillosis

Blood Glucose Meter - Novel glucometer auto-corrects hematocrit measurement

Blood Tests - Phlebotomy contributes to anemia in hospitalized patients

Bone Marrow - Osteopontin and sialoprotein expression studied, effect of fluid flow shown

Business & Finance - Biopharmaceutical company reports second quarter 2005 results

Business & Finance - Biosciences company secures $35 million line of credit from California bank

Business Update - Company to amend EP-2104R clinical trial protocols

Cancer Risk Factors - Hepatitis B virus-associated liver cancer harbors c-kit-positive tumor cells

Cancer Risk Factors - Links between systemic lupus erythematosus and cancer explored

Cancer Survivors - Chromosome analysis performed in childhood cancer survivors and their offspring

Cardioprotection - PARP is a pathophysiological modulator of cardiac myocyte injury

Cardiovascular Disease - Women unaware of differences in bad and good cholesterol, survey shows

Chlamydia Infection - Infected cells upregulate host innate antimicrobial response to chlamydia

Chronic Myeloid Leukemia - ABL mutations associated with greater risk of blast crisis and shorter survival

Clinical Trials - Phase 2 clinical trial for hemoglobin-based blood alternative Hemospan initiated

Coagulation - Factor IX recognition studied, need for factor XIa demonstrated

Colon Cancer - Carcinoma of colon presented as fever of unknown origin

Corynebacterium Infection - High prevalence of ulcerative posthitis in rams associated with legume-rich diet

Cryptococcus Neoformans - TGF-beta prevents eosinophilic lung disease but impairs pathogen clearance

Cyclospora Cayetanensis - Flow cytometry detects Cyclospora cayetanensis oocytes in fecal specimens

Diagnostics - Company launches minimal residual disease test for common leukemia

Diagnostics - Respiratory pathogens rapidly identified/typed for epidemic surveillance

Diagnostics - TaqMan-based 1-step PCR assay rapid and sensitive for norovirus detection

Diagnostics - U.S. distribution partner for heart, blood vessel assessment device announced

Diet & Nutrition - Vitamin K-dependent protein S studied, Ca²⁺-binding clarified

Drug Development - Drug developer sets $15 million financing, renin inhibitor collaboration

Drug Development - Merck reaches clinical development milestone with adenovirus vaccine candidate

Drug Development - U.S. NIH awards $1.49 million grant to prepare blood clot drug for human trials

Embolisms - Safety of D-dimer test to diagnose suspected acute pulmonary embolism assessed

Embryonic Stem Cell Research - Stable mixed chimerism induction by ESCs requires functional Fas/fasl engagement

Endocrinology - New hemochromatosis mutants can't pump iron

Epstein-Barr Virus - HSP90 expression in EBV-infected B cells promotes gammadelta T-cell growth

Epstein-Barr Virus - Healthy EBV carriers have detectable Rta-specific CD8+ cells restricted by B2704

Fetal Loss Risk Factors - Elevated factor VII is risk factor for recurrent fetal loss

Finance - Cancer-, blood-focused pharmaceutical company reports Q2 2005 financial results

Finance - Cord blood bank company reports 12% increase in revenue

Finance - Immune-based biopharmaceutical corporation signs $15 million financing agreement

Finance - Umbilical cord blood stem cell bank-focused company completes round of financing

Finance - Vascular device company announces profitability and record Q2 2005 results

Genetics & Genomics - Genes are found to be upregulated in preeclampsia

Geriatrics - The elderly require lower initiation and maintenance doses of warfarin

Glioma - Low-molecular weight caldesmon a potential serum marker for glioma

HIV-1-Associated Dementia - HIV dementia related to changes in molecular factors involved in infection

HIV-1/Tuberculosis Coinfection - Serum neopterin highly elevated in HIV/TB coinfection + CD4 <200/mm³

HIV/AIDS Diagnostics - Evolving technologies for HIV diagnostics benefit resource-limited areas

HIV/AIDS Diagnostics - Low-cost assays available to monitor HAART in resource-poor settings

HIV/AIDS Diagnostics - Total lymphocyte count helps predict low CD4 count in low-resource setting

HIV/AIDS Drug Development - Antigene PNA targeted to proviral HIV-1 DNA inhibits viral replication

HIV/AIDS Drug Development - Fermented P. tinctorium Aiton extract suppresses acute HIV-1 infection

HIV/AIDS Drug Development - Measles virus inhibits HIV-1 replication in lymphoid tissues

HIV/AIDS Drug Development - New drug targets for HIV needed

HIV/AIDS Drug Development - Peptides derived from HIV-1 RT are inhibitors of the viral integrase

HIV/AIDS Drug Development - Peptides derived from HIV-1 reverse transcriptase inhibit viral integrase

HIV/AIDS Drug Development - Small molecule inhibitor of ATM kinase suppresses drug-resistant HIV-1 infection

HIV/AIDS Drug Development - Thymidine analogue derivatives suppress multidrug-resistant HIV-1 RT

HIV/AIDS Drug Development - Tn5 transposase target screen identifies HIV-1 inhibitors

HIV/AIDS Education - Individuals in Iran have fairly good AIDS-related knowledge

HIV/AIDS Epidemiology - HIV-1 subtype C/HIV-2 subtype A are major subtypes circulating in south India

HIV/AIDS GBV-C Coinfection - Prevalence of Gb virus C in perinatally HIV-infected children is small

HIV/AIDS HAART - Changing treatment indications contributed to improved survival in HIV/AIDS

HIV/AIDS HAART - Continuous saquinavir treatment progressively suppresses HIV-1 expression

HIV/AIDS HAART - GIQ predicts virologic response among patients with at least 3 PI mutations

HIV/AIDS Immunology - Orchestrated action of different immune mechanisms decide HIV infection outcome

HIV/AIDS Mathematical Model - B-spline model studies multiple longitudinal biomarkers/survival in HIV/AIDS

HIV/AIDS Pathogenesis - HIV-1 Vpr plays active role in viral offensive strategies

HIV/AIDS Pathogenesis - HIV-1 uncoating requires cellular activation

HIV/AIDS Pathogenesis - Innate-immunity effector cells marker of CD4+ cell loss in pediatric HIV/AIDS

HIV/AIDS Pathogenesis - SEN virus seroprevalence in HIV+ patients linked to HIV-replication

HIV/AIDS Pediatrics - HIV-infected children have poorer qualitative antibody response to PnCV

HIV/AIDS Pediatrics - Population-specific infant mortality rates guide HIV and infant feeding policy

HIV/AIDS Research - HAART suppresses viral load in macaques infected with RT-SHIV