Cerebrospinal Meningitis

Meningococcal prophage may promote epidemic N. meningitidis clone

Published in Blood Weekly, September 1st, 2005

A meningococcal prophage may promote the development of an epidemic Neisseria meningitidis clone.

"Cerebrospinal meningitis is a feared disease that can cause the death of a previously healthy individual within hours. Paradoxically, the causative agent, Neisseria meningitidis, is a common inhabitant of the human nasopharynx, and as such, may be considered a normal, commensal organism," scientists writing in the Journal of Experimental Medicine report.

"Only in a small proportion of colonized people do the bacteria invade the bloodstream, from where they can cross the blood-brain barrier to cause meningitis.

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Source: Blood Weekly (2005-09-01)

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