Skin Cancer
CD8+ and CD4+ lymphocytes contribute to immunosurveillance against skin cancer
Published in Blood Weekly, September 8th, 2005
According to recent research from the United States, "Immunosuppressed patients are extremely susceptible to cutaneous squamous cell carcinoma, suggesting that immunosurveillance by T lymphocytes protects against this ultraviolet radiation-induced tumor.
"To determine the relative contribution of CD8+ and CD4+ lymphocytes to immunosurveillance, we tested the effects of CD8+ or CD4+ T lymphocyte depletion on the susceptibility of C3H/HeN mice to a syngeneic UVR-induced skin tumor cell line."
"Both anti-CD8 and anti-CD4 treatment significantly enhanced...
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Source: Blood Weekly (2005-09-08)
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