Apoptosis

Novel polysaccharide induced apoptosis in HL-60 cells

Published in Blood Weekly, September 8th, 2005

A novel polysaccharide isolated from the mucus of the loach Misgurnus anguillicaudatus (MAP) induced apoptosis in HL-60 cells.

According to recent research from China, "This study was designed to determine the anti-proliferative, apoptotic properties of a novel polysaccharide from the loach, MAP, using a human promyelocytic leukemia line (HL-60) as a model system. HL-60 cells were cultured in the presence of MAP at various concentrations (50-800 mg/l) for 5 days and the percentage of cell viability was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay."

"The results showed that MAP inhibited the cells...

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Source: Blood Weekly (2005-09-08)

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