Published in Blood Weekly, September 8th, 2005
According to a recent review from England, "The emerging understanding of the biology of the hemopoietic stem cell is beginning to shed light on the mechanisms by which benzene gives rise to acute myeloid leukemia.
"These mechanisms are complex, affecting not only the DNA, but also the complex intercellular interactions present in the bone marrow microenvironment."
"The toxic effects of benzene are mediated within the bone marrow and we are beginning to understand the contributions of interindividual variation in xenobiotic metabolisms and DNA...
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Source: Blood Weekly (2005-09-08)
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