Histamine
Study investigated whether histamine induces TF expression in vascular cells
Published in Blood Weekly, September 15th, 2005
According to researchers in Switzerland, "Histamine can induce coronary vasospasm, leading to variant angina and acute myocardial infarction. However, the role of histamine in thrombus formation is ill defined. Hence, [our] study investigates whether histamine induces tissue factor (TF) expression in vascular cells."
J. Steffel and colleagues of the University of Zurich reported, "Histamine (10-8 to 10-5 mol/L) induced TF expression in a concentration-dependent manner in human aortic endothelial and vascular smooth muscle cells, whereas...
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Source: Blood Weekly (2005-09-15)
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