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Blood Weekly

Susan Hasty, Publisher

Table of Contents . . . October 20th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Blood Weekly | Other Publications

Hematology - Procoagulant complex studied, molecular models constructed

Leukemia - Effects of sample source and test methodology on prognosis of AML examined

Stem Cell Research - NFAT and Osterix cooperatively regulate bone formation

Stem Cell Transplantation - Corneal epithelial cell and corneal SC transplants survive 1-year postsurgery

Tissue Engineering - Matrix composition has an important role in embryonic stem cell development

Acute Myeloid Leukemia - BMI-1 is highly expressed in MO-subtype acute myeloid leukemia

Acute Myeloid Leukemia - New findings in the area of acute myeloid leukemia described

Angiology - Coatings of HA-Ti, AA-Ti or LA-Ti reduced platelet adhesion to titanium metal

Angiology - Platelet activation analyzed, role of hepatocyte growth factor revealed

Angiology - Study shows blood clots from venous thrombosis kill over 500,000 in E.U. yearly

Atherosclerosis - Recent findings in atherosclerosis provide new insights

Leukemia - Researchers describe findings in leukemia studies

Awards - Dr. Woo-Suk Hwang receives Indispensable Person in Health Award

Biofilms - Methods for the treatment and opinion prevention of bacterial biofilms reviewed

Biomedical Engineering - New data illuminates research in biomedical engineering

Biomedical Research - Vascular biology in urgent need of support

Breast Cancer - HIF-1 alpha overexpression predicts early breast cancer relapse

Breast Cancer - Trial shows epoetin alfa use to maintain Hb resulted in decreased survival

Stem Cell Research - New findings in the area of stem cell detailed

Cancer Therapy - Clinical effect of imatinib in acute lymphoblastic leukemia assessed

Cancer Therapy - Cyclooxygenase inhibitors modulate NK activities that control metastatic disease

Cancer Therapy - Researchers report details of new studies and findings in the area of cancer therapy

Cancer Therapy - U.S. FDA expands Neulasta label

Cardiology - Two new treatment advances in coronary artery disease announced at meeting

Clinical Trials - Three new phase I trials launched for compounds XL844, XL184, and XL784

Collaborations - Alliance to develop longer acting forms of blood clotting factors

Collaborations - Collaboration on nephrology applications of CDK inhibitors announced

Colorectal Cancer - Guaiac, immunochemical fecal occult blood tests both show high yield of neoplasia

Dental Implants - Platelet-rich plasma promotes osteoblast proliferation

Diabetes Complications - Recovery time from Bell palsy is longer for those with diabetes

Diagnostics - GC-MS detects prenatal exposure to environmental toxicants and their metabolites

Diagnostics - Magnetic resonance imaging used to select patients for repeated embolization

End-Stage Heart Failure - VentrAssist LVAD shows promise for permanent implantation

Extracorporeal Circulation - Effects of hypothermia on microcirculation characterized

Finance - Maker of blood clot imaging product reports year end finances

Fitness & Wellness - Endurance training boosts endothelial progenitors in heart disease patients

Geriatrics - Cerebral vein and dural sinus thrombosis described in elderly patients

Heart Transplantation - Routine postoperative prostate cancer screening recommended after heart transplant

Hematology - Activated platelets analyzed, cytoskeleton translocation clarified

Hematology - Clinical studies recommend capsule endoscopy as diagnostics tool for ID anemia

Hematology - New findings in hematology described

Heparin - Polymeric coatings with both nitric oxide release and immobilized active heparin studied

Hypertension - First report out on cancer drug Gleevec as therapy for pulmonary hypertension

Hypertension - Gene therapy to be used to lower blood pressure

Ischemia - Research in ischemia provides new insights

Kidney Transplantation - Researchers publish new studies and findings in the area of kidney transplantation

Leukemia - Data from phase III trial of Genasense confirm extended durability of remission

Leukemia - Higher blast percentage in circulation than bone marrow implied worse prognosis

Leukemia - Management of chronic myeloid leukemia in France assessed

Leukemia - Reports add new data to leukemia research

Leukemia - Xanthoangelol induced apoptosis in neuroblastoma and leukemia cells

Lymphoma - STAT5 is a modifier of interleukin-7-induced lymphomas

Malaria - Intermittent prophylaxis shown to prevent malaria in infants

Malaria - The best malaria drugs are not being used in Africa

Metastatic Melanoma Prognostic Indicator - Elevated neutrophils/monocytes associated with poor metastatic melanoma survival

Multiple Myeloma - Independent phase I/II study of Defibrotide begins

Myelodysplastic Syndrome - Studies advance knowledge in myelodysplastic syndrome research

Neurogenesis - Studies add new findings to neurogenesis body of knowledge

Normal Pressure Hydrocephalus - First clinical guidelines for diagnosing and treating NPH established

Oncology - Therapies targeting angiogenic protein receptors may treat leukemia

Oral Health - Nicotine inhibits myofibroblast differentiation in gingival fibroblasts

Patents - Oximetry devices maker to pay about $280 million charge for patent infringement

Pediatric Cancer - Bone marrow involvement in pediatric anaplastic large cell lymphoma studied

Pediatric Leukemia - Evidence for single-step mechanism in origin of childhood ALL revealed

Pediatric Leukemia - Neoplastic disorders of hematopoiesis in children with Down syndrome discussed

Peripheral Arterial Occlusion - Alfimeprase shows promise in phase I clinical trial

Pharmaceutical Research - Effect of anticoagulant drugs in cancer examined

Physiology - Prion protein studied, behavior in platelet activation defined

Portal Hypertension - Researchers uncover mechanisms that can lead to portal hypertension

Postpartum Hemorrhage - A new strategy could prevent a leading cause of maternal death in Africa

Renal/Adrenal Surgery - Laparoscopic surgery feasible for patients on oral anticoagulants

Sleep Apnea - Researchers examine effectiveness of new home test for sleep apnea

Spectroscopy - Sugar intermediates of pentose phosphate pathway quantified by LC-MS/MS

Stem Cell Research - A newly recognized CD14+ subset may be valuable for vascular repair

Stem Cell Research - CD144 is transiently expressed by fetal liver hematopoietic stem cells

Stem Cell Research - Conditional telomerase induction causes proliferation of hair follicle SCs

Stem Cell Research - ERM required for transcriptional control of spermatogonial stem cell niche

Stem Cell Research - Embryonic SCs transplanted in injured brain generate nerve and vascular cells

Stem Cell Research - Histone deacetylases have role in regulation of erythroid cell differentiation

Stem Cell Research - MGH investigations will focus on the impact of the stem cell environment

Stem Cell Research - Mesenchymal SCs recruited to striated muscle by NFAT/IL-4-mediated cell fusion

Stem Cell Research - New findings in the area of stem cell described

Stem Cell Research - Rybp/DEDAF required for early postimplantation and CNS development

Stem Cell Research - SSCs change cell-surface molecule expression patterns in postnatal development

Stem Cell Research - Shc3 affects human high-grade astrocytomas survival

Stem Cell Research - TAZ protein modulates mesenchymal stem cell differentiation

Stem Cell Transplantation - Selective depletion of alloreactive donor lymphocytes reduces GVHD severity

Stroke - Rural telestroke network allows rapid, safe use of tissue plasminogen activator

Thalassemia - Study shows common form of thalassemia can be managed without blood transfusion

Thromboembolism - Low-molecular-weight heparin prevented postoperative venous thromboembolism

Thromboembolism - Prophylaxis of thromboembolic events during urologic surgery advised

Thromboembolism - Venous perioperative thromboembolism prophylaxis suggested

Tissue Engineering - RGD peptide-conjugated magnetite cationic liposomes used for tissue engineering

Tissue Engineering - Recent findings illuminate research in tissue engineering

Tissue Engineering - Scaffold facilitates cartilage repair after microfracture

Transplant Medicine - Epigallocatechin gallate reduces cyclosporine-induced hemolysis

Transplant Medicine - Liver disease scores summarize liver transplant outcomes

Transplant Medicine - Microcirculatory aberrations are common in cardiac transplant recipients

Transplant Medicine - Valganciclovir suitable for treatment of CMV infection and disease

Virology - Dengue virus NS1 studied, fate of secreted form defined

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